[HTML][HTML] AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages

L Xia, C Zhang, N Lv, Z Liang, T Ma, H Cheng, Y Xia… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Aberrant activation of macrophages with mitochondria dismiss was proved to be
associated with pathogenesis of ALI (acute lung injury). Exosomes from adipose-derived …

Effects of medicinal plants and phytochemicals in Nrf2 pathways during inflammatory bowel diseases and related colorectal cancer: A comprehensive review

LF Laurindo, MC de Maio, G Minniti, N de Góes Corrêa… - Metabolites, 2023 - mdpi.com
Inflammatory bowel diseases (IBDs) are related to nuclear factor erythroid 2-related factor 2
(Nrf2) dysregulation. In vitro and in vivo studies using phytocompounds as modulators of the …

Recent advances in cellular signaling interplay between redox metabolism and autophagy modulation in cancer: an overview of molecular mechanisms and …

MA Rahman, KR Ahmed, F Haque, MN Park, B Kim - Antioxidants, 2023 - mdpi.com
Autophagy is a fundamental homeostatic process in which certain cellular components are
ingested by double-membrane autophagosomes and then degraded to create energy or to …

[HTML][HTML] Hepatoprotective effects of astragalin against polystyrene microplastics induced hepatic damage in male albino rats by modulating Nrf-2/Keap-1 pathway

A Hamza, MU Ijaz, N Ehsan, HA Khan… - Journal of Functional …, 2023 - Elsevier
The current study was designed to determine the curative potential of astragalin (AST)
against polystyrene microplastics (PS-MPs) induced hepatic toxicity in rats. PS-MPs …

[HTML][HTML] Ginsenoside Rg1 alleviates ANIT-induced cholestatic liver injury by inhibiting hepatic inflammation and oxidative stress via SIRT1 activation

Q Gao, G Li, Y Zu, Y Xu, C Wang, D Xiang, W He… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Ginseng (Panax ginseng CA Mey) is a common
traditional Chinese medicine used for anti-inflammation, treating colitis, type 2 diabetes …

Ginseng polysaccharide reduces autoimmune hepatitis inflammatory response by inhibiting PI3K/AKT and TLRs/NF-κB signaling pathways

X Qi, X Lu, Y Han, Y Xing, Y Zheng, C Cui - Phytomedicine, 2023 - Elsevier
Background Ginseng polysaccharides (GP) have been found to exhibit significant immune
regulatory effects, making them a promising candidate for treating immune-related diseases …

Design, synthesis fusidic acid derivatives alleviate acute lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway

Z Liu, X Huang, HY Guo, LW Zhang, YS Quan… - European Journal of …, 2023 - Elsevier
Acute lung injury (ALI) refers to a series of lung lesions resulting from multiple lung injuries,
even leading to morbidity and death, abundant previous reports have showed that anti …

The protective effects of ginseng polysaccharides and their effective subfraction against dextran sodium sulfate-induced colitis

S Li, X Huo, Y Qi, D Ren, Z Li, D Qu, Y Sun - Foods, 2022 - mdpi.com
Polysaccharides from Panax ginseng are natural carbohydrates with multiple activities.
However, little was known about its functions on colitis. In this study, we aim to investigate …

Preventive effect of Atractylodis Rhizoma extract on DSS-induced acute ulcerative colitis through the regulation of the MAPK/NF-κB signals in vivo and in vitro

X Lin, X Guo, L Qu, J Tu, S Li, G Cao, Y Liu - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Atractylodes lancea (Thunb.) DC. is traditionally
used as a folk medicine for treating gastrointestinal diseases in China. Nevertheless, the …

Genes and regulatory mechanisms for ginsenoside biosynthesis

P Mohanan, TJ Yang, YH Song - Journal of Plant Biology, 2023 - Springer
Panax ginseng is a medicinal plant belonging to the Araliaceae family. Ginseng is known as
the king of oriental medicine, which has been practiced since ancient times in East Asian …