Platelet activation plays an important role in the development of sepsis. During sepsis,
platelet activation leads to endothelial cell injury and promotes neutrophil extracellular trap …

Antiplatelet drugs serve as a first-line antithrombotic therapy for the management of acute
ischemic events and the prevention of secondary complications in vascular diseases …

Therapeutic peptides are oligomers or short polymers of amino acids used for various
medical purposes. Peptide-based treatments have evolved considerably due to new …

Decades after the introduction of oral anti-coagulants namely the vitamin K antagonist (VKA)
Warfarin and antiplatelet agents such as Aspirin and Plavix, new classes of direct, small …

Since isoxazole and triazole have significant applications in pharmaceutical chemistry, the
synthesis of hybrid isoxazole‐triazole molecules has attracted great attention. In the present …

We report a case of significant pulmonary hemorrhage developing shortly after commencing
ticagrelor and aspirin therapy and requiring coronary artery bypass grafting to safely cease …

Quantitative proton NMR (qHNMR) methodology was employed for the stoichiometric (free
base and the corresponding counterion) assessment of a ticagrelor process impurity, also …

In total, 97 acute ST-segment elevation myocardial infarction (STEMI) patients who received
an emergency percutaneous coronary intervention (PCI) were enrolled and divided into a …

Objective: An analytical assay with focus on UV spectrophotometric method was proposed
as alternative for the analysis of the antiplatelet ticagrelor. Method: Method performance was …

Objectives: The objectives of this study were to evaluate the bioequivalence and safety
profiles of the test drug and reference drug of 90 mg ticagrelor tablets under fasting …