[HTML][HTML] Engineering protein nanocages as carriers for biomedical applications

S Bhaskar, S Lim - NPG Asia materials, 2017 - nature.com
Protein nanocages have been explored as potential carriers in biomedicine. Formed by the
self-assembly of protein subunits, the caged structure has three surfaces that can be …

The OmpA family of proteins: roles in bacterial pathogenesis and immunity

AW Confer, S Ayalew - Veterinary microbiology, 2013 - Elsevier
The OmpA family of outer membrane proteins is a group of genetically related, heat-
modifiable, surface-exposed, porin proteins that are in high-copy number in the outer …

A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells

G Stary, A Olive, AF Radovic-Moreno, D Gondek… - Science, 2015 - science.org
INTRODUCTION Administering vaccines through nonmucosal routes often leads to poor
protection against mucosal pathogens, presumably because such vaccines do not generate …

Update on Chlamydia trachomatis vaccinology

LM de la Maza, G Zhong… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Attempts to produce a vaccine to protect against Chlamydia trachomatis-induced trachoma
were initiated more than 100 years ago and continued for several decades. Using whole …

CD4+ T cells are necessary and sufficient to confer protection against Chlamydia trachomatis infection in the murine upper genital tract

DC Gondek, AJ Olive, G Stary… - The Journal of …, 2012 - journals.aai.org
Chlamydia trachomatis infection is the most common bacterial sexually transmitted disease
in the United States. Chlamydia infections that ascend to the upper genital tract can persist …

Genital Chlamydia trachomatis: understanding the roles of innate and adaptive immunity in vaccine research

S Vasilevsky, G Greub… - Clinical microbiology …, 2014 - Am Soc Microbiol
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted disease
worldwide, and despite significant advances in chlamydial research, a prophylactic vaccine …

Evaluation of tandem Chlamydia trachomatis MOMP multi-epitopes vaccine in BALB/c mice model

P Jiang, Y Cai, J Chen, X Ye, S Mao, S Zhu, X Xue… - Vaccine, 2017 - Elsevier
Chlamydia trachomatis (Ct), an obligate intracellular parasite, is the leading cause of
bacterial sexually transmitted diseases worldwide. The best solution to control the spread of …

Animal models for studying female genital tract infection with Chlamydia trachomatis

E De Clercq, I Kalmar, D Vanrompay - Infection and immunity, 2013 - Am Soc Microbiol
Chlamydia trachomatis is a Gram-negative obligate intracellular bacterial pathogen. It is the
leading cause of bacterial sexually transmitted disease in the world, with more than 100 …

Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go?

LM de la Maza, TL Darville, S Pal - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. Antibiotic treatment does not prevent against reinfection and a …

Protection Against Chlamydia trachomatis Infection and Upper Genital Tract Pathological Changes by Vaccine-Promoted Neutralizing Antibodies Directed to the VD4 …

AW Olsen, F Follmann, K Erneholm… - The Journal of …, 2015 - academic.oup.com
The VD4 region from the Chlamydia trachomatis major outer membrane protein contains
important neutralizing B-cell epitopes of relevance for antibody-mediated protection against …