Neurons in sensory ganglia are surrounded by satellite glial cells (SGCs) that perform
similar functions to the glia found in the CNS. When primary sensory neurons are injured …

Neuroplastic changes in the neuronal networks involving the trigeminal ganglion (TG),
trigeminal spinal subnucleus caudalis (Vc), and upper cervical spinal cord (C1/C2) are …

Peripheral tissue injury/inflammation can alter the properties of somatic sensory pathways,
resulting in behavioral hypersensitivity and pathological and/or chronic pain, including …

Peripheral nerve injury activates satellite cells to produce interleukin 1β (IL-1β) which
mediates inflammation and hyperalgesia. This study investigated the hypothesis that …

Previous studies in several different trigeminal nerve injury/inflammation models indicated
that the hyperexcitability of primary afferent neurons contributes to the pain pathway …

BACKGROUND AND OBJECTIVES: Satellite glial cells in sensory ganglia are a recent
subject of research in the field of pain and a possible therapeutic target in the future …

Neuropathic and inflammatory pain are major clinical challenges due to their ambiguous
mechanisms and limited treatment approaches. N-methyl-D-aspartate receptor (NMDAR) …

A number of membrane lipid-derived mediators play pivotal roles in the initiation,
maintenance, and regulation of various types of acute and chronic pain. Acute pain …

Inflammatory orofacial pain, in which substance P (SP) plays an important role, is closely
related to the cross-talk between trigeminal ganglion (TG) neurons and satellite glial cells …

Inflammation suppresses satellite glial inward rectifying K+(Kir) currents in the trigeminal
ganglia. Kir channel may be a potential therapeutic target for treatment of pain. ABSTRACT …