Nonalcoholic fatty liver disease (NAFLD) is now the most frequent chronic liver disease in
Western societies, affecting one in four adults in the USA, and is strongly associated with …

Objective Aberrant ketogenesis is correlated with the degree of steatosis in non-alcoholic
fatty liver disease (NAFLD) patients, and an inborn error of ketogenesis (mitochondrial HMG …

Background Nonalcoholic fatty liver disease (NAFLD) usually includes NAFL called simple
hepatosteatosis and nonalcoholic steatohepatitis (NASH) called more steatohepatitis. The …

Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent, and potentially morbid,
disease that affects one-third of the US population. Normal liver safely accommodates lipid …

Phosphoenolpyruvate carboxykinase (PEPCK or PCK) catalyzes the first rate-limiting step in
hepatic gluconeogenesis pathway to maintain blood glucose levels. Mammalian cells …

Significance: Current lifestyles with high-energy diets and little exercise are triggering an
alarming growth in obesity. Excess of adiposity is leading to severe increases in associated …

Background Mitochondrial oxidative function plays a key role in the development of non-
alcoholic fatty liver disease (NAFLD) and insulin resistance (IR). Recent studies reported …

Recent data increasingly support a complex interplay between the metabolic condition
diabetes mellitus and the pathologically defined nonalcoholic fatty liver disease (NAFLD) …

In parallel with the obesity epidemic, nonalcoholic fatty liver disease (NAFLD) has emerged
as the most common chronic liver disease worldwide. Disequilibrium of lipid metabolism and …

Hepatic steatosis, the first step in the progression of nonalcoholic fatty liver disease, is
characterized by triglyceride accumulation in hepatocytes and is highly prevalent in people …