Targeted over-expression of PPARγ in pig skeletal muscle improves oxidative fiber formation and intramuscular fat deposition

H Gu, Y Zhou, J Yang, J Li, Y Peng, X Zhang, Y Miao… - bioRxiv, 2020 - biorxiv.org
PPARγ is a master regulator of adipogenesis and lipogenesis. To understand its roles in fat
deposition and fiber formation in skeletal muscle, we successfully generated muscle-specific …

[HTML][HTML] Exploration of the Molecular Mechanism for Lipoprotein Lipase Expression Variations in SH-SY5Y Cells Exposed to Different Doses of Amyloid-Beta Protein

J Zhang, Y Liu, S Wang, R Que, W Zhao… - Frontiers in Aging …, 2020 - frontiersin.org
Progressive accumulation of amyloid-β (Aβ) plaques in the brain is a characteristic
pathological change in Alzheimer's disease (AD). We previously found the expression of …

[图书][B] Cellular and Molecular Targets in the Neuroendocrine System that Defend against Diabetes, Obesity, and Alzheimer's Disease

AM Reilly - 2021 - search.proquest.com
Metabolic survival mechanisms that defend body weight and conserve energy are currently
at odds with modernized society which has a food supply that is ubiquitous, calorie dense …

The Effect of Early Dietary Intervention on Alzheimer's Disease-Related Pathology and Cognitive Function in Mice

A Amelianchik - 2022 - digitalcommons.rockefeller.edu
Alzheimer's disease (AD) is a fatal cognitive disorder with proteinaceous brain deposits,
neuroinflammation, cerebrovascular dysfunction, and extensive neuronal loss. AD is a …

[PDF][PDF] Dexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer's disease in metabolically stressed APPswe/PS1dE9 mice

PR Manzine, T Espinosa‑Jimenez… - 2021 - cellandbioscience.biomedcentral …
Background: Several studies stablished a relationship between metabolic disturbances and
Alzheimers disease (AD) where inflammation plays a pivotal role. However, mechanisms …

Reactive Oxygen Species Promote the Formation of Mtb-Induced Foamy Macrophages by Downregulating the Expression of Peroxisome Proliferator-Activated …

JM Li, J Liu, Y Ye, L Zhang, Y Gao, J Rao, R Su… - Qing and Huang, Zikun … - papers.ssrn.com
Inducing the formation of foamy macrophages is one of the important mechanisms for
Mycobacterium tuberculosis (MTB) to escape immune killing and achieve its long-term …

[PDF][PDF] Avances en medicina traslacional para entender mecanismos de la salud y el tratamiento de enfermedades complejas

GP Alva, LP Martínez - biotecmov.ibt.unam.mx
Desde hace tiempo, el enfoque analítico reduccionista en la investigación científica ha
permitido avances significativos en el entendimiento de las funciones de los órganos y …

[PDF][PDF] impairment and neuroinflammation via inhibition on NF-κB signaling in Alzheimer's

B Forsythoside - 2020 - jneuroinflammation.biomedcentral …
Background: Neuroinflammation is a principal element in Alzheimer's disease (AD)
pathogenesis, so anti-inflammation may be a promising therapeutic strategy. Forsythoside B …