The transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel that is
activated by capsaicin (CAP), the main component of chili pepper. Despite studies in several …

Abstract Ethnopharmacological relevance Schisandra chinensis (Turcz.) Baill (S.
Chinensis), a traditional Chinese medicine frequently used in the traditional treatment of …

Adipose tissue is an active metabolic organ that contributes to processes such as energy
storage and utilization and to the production of a number of metabolic agents, such as …

Paclitaxel-induced neuropathic pain (PINP) is a dose-limiting side effect and is refractory to
widely used analgesic drugs. Previous studies have demonstrated a protective role of …

Malvaceae family is typical from the Mediterranean region, contains 240 genera and more
than 4,200 species. They are most commonly used as ornamental plants, although they can …

Brain pericytes regulate cerebral blood flow, maintain the integrity of the blood-brain barrier
(BBB), and facilitate the removal of amyloid β (Aβ), which is critical to healthy brain activity …

Scopoletin is a coumarin synthesized by diverse medicinal and edible plants, which plays a
vital role as a therapeutic and chemopreventive agent in the treatment of a variety of …

Background Neuroinflammation following peripheral surgery plays a key role in
postoperative cognitive dysfunction (POCD) development and there is no effective therapy to …

Alzheimer's disease (AD) is the most common form of senile dementia and is characterized
by progressive cognitive impairment and neuronal degeneration. Microglial activation is an …

The intricate nature of Alzheimer's disease (AD) pathogenesis poses a persistent obstacle to
drug development. In recent times, neuroinflammation has emerged as a crucial pathogenic …