[HTML][HTML] Duhuo Jisheng decoction alleviates neuroinflammation and neuropathic pain by suppressing microglial M1 polarization: a network pharmacology research
C Gao, Y Zhao, T Yang, X Gao, C Meng - Journal of Orthopaedic Surgery …, 2023 - Springer
Background Neuropathic pain (NP) is the most prevalent form of chronic pain resulting from
nerve damage or injury. Despite the widespread use of Duhuo Jisheng decoction (DHJSD) …
nerve damage or injury. Despite the widespread use of Duhuo Jisheng decoction (DHJSD) …
Rosiglitazone Alleviates Mechanical Allodynia of Rats with Bone Cancer Pain through the Activation of PPAR‐γ to Inhibit the NF‐κB/NLRP3 Inflammatory Axis in …
J Fu, B Zhao, C Ni, H Ni, L Xu, Q He, M Xu… - PPAR …, 2021 - Wiley Online Library
Bone cancer pain (BCP) is a serious clinical problem that affects the quality of life of cancer
patients. However, the current treatment methods for this condition are still unsatisfactory …
patients. However, the current treatment methods for this condition are still unsatisfactory …
[HTML][HTML] Studies on the mechanism of Toxoplasma gondii Chinese 1 genotype Wh6 strain causing mice abnormal cognitive behavior
Q Tao, D Yang, K Qin, L Liu, M Jin, F Zhang, J Zhu… - Parasites & …, 2023 - Springer
Background Alzheimer's disease presents an abnormal cognitive behavior. TgCtwh6 is one
of the predominant T. gondii strains prevalent in China. Although T. gondii type II strain …
of the predominant T. gondii strains prevalent in China. Although T. gondii type II strain …
Bis (ethylmaltolato) oxidovanadium (IV) attenuates amyloid-beta-mediated neuroinflammation by inhibiting NF-κB signaling pathway via a PPARγ-dependent …
Z He, X Li, S Han, B Ren, X Hu, N Li, X Du, J Ni… - Metallomics, 2021 - academic.oup.com
Neuroinflammation plays a pivotal role in the pathophysiology of neurodegenerative
diseases, such as Parkinson's disease and Alzheimer's disease. During brain …
diseases, such as Parkinson's disease and Alzheimer's disease. During brain …
[HTML][HTML] The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury
Y Zhao, T Li, Z Jiang, C Gai, S Yu, D Xin… - Neural Regeneration …, 2024 - journals.lww.com
We previously showed that hydrogen sulfide (H 2 S) has a neuroprotective effect in the
context of hypoxic ischemic brain injury in neonatal mice. However, the precise mechanism …
context of hypoxic ischemic brain injury in neonatal mice. However, the precise mechanism …
[HTML][HTML] Metabolic defects caused by high-fat diet modify disease risk through inflammatory and amyloidogenic pathways in a mouse model of Alzheimer's disease
High-fat diet (HFD) has been shown to accelerate Alzheimer's disease (AD) pathology, but
the exact molecular and cellular mechanisms remain incompletely understood. Moreover, it …
the exact molecular and cellular mechanisms remain incompletely understood. Moreover, it …
[HTML][HTML] Therapeutic Candidates for Alzheimer's Disease: Saponins
R Zhang, M Zeng, X Zhang, Y Zheng, N Lv… - International Journal of …, 2023 - mdpi.com
Drug development for Alzheimer's disease, the leading cause of dementia, has been a long-
standing challenge. Saponins, which are steroid or triterpenoid glycosides with various …
standing challenge. Saponins, which are steroid or triterpenoid glycosides with various …
The Potential Effects of Isoleucine Restricted Diet on Cognitive Impairment in High‐Fat‐Induced Obese Mice via Gut Microbiota–Brain Axis
Y Wang, X Rong, H Guan, F Ouyang… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Obesity induced by high‐fat diet (HFD) can cause lipid metabolism disorders and
cognitive impairment. Isoleucine restriction can effectively alleviate lipid metabolism …
cognitive impairment. Isoleucine restriction can effectively alleviate lipid metabolism …
[HTML][HTML] The moringin/α-CD pretreatment induces neuroprotection in an in vitro model of Alzheimer's disease: A transcriptomic study
S Silvestro, L Chiricosta, A Gugliandolo, R Iori… - Current Issues in …, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and represents the
most common form of senile dementia. Autophagy and mitophagy are cellular processes …
most common form of senile dementia. Autophagy and mitophagy are cellular processes …
[HTML][HTML] Alzheimer's disease, a metabolic disorder: Clinical advances and basic model studies
S Zhou, L Tu, W Chen, G Yan… - Experimental and …, 2024 - spandidos-publications.com
Alzheimer's disease (AD) is a type of neurodegenerative disease characterized by cognitive
impairment that is aggravated with age. The pathological manifestations include …
impairment that is aggravated with age. The pathological manifestations include …