Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

Fluorescent probes for the detection of disease-associated biomarkers

WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Engineered NIR-II fluorophores with ultralong-distance molecular packing for high-contrast deep lesion identification

Z Feng, Y Li, S Chen, J Li, T Wu, Y Ying… - Nature …, 2023 - nature.com
The limited signal of long-wavelength near-infrared-II (NIR-II, 900–1880 nm) fluorophores
and the strong background caused by the diffused photons make high-contrast fluorescence …

A dual‐locked activatable phototheranostic probe for biomarker‐regulated photodynamic and photothermal cancer therapy

X Wei, C Zhang, S He, J Huang… - Angewandte Chemie …, 2022 - Wiley Online Library
Activatable phototheranostics holds promise for precision cancer treatment owing to the
“turn‐on” signals and therapeutic effects. However, most activatable phototheranostic …

Near‐infrared photodynamic chemiluminescent probes for cancer therapy and metastasis detection

J Huang, C Zhang, X Wang, X Wei… - Angewandte Chemie, 2023 - Wiley Online Library
There is growing interest in the development of chemiluminescence (CL) probes for
phototheranostics because of their minimized tissue autofluorescence. However, due to a …

Fluorescence image-guided tumour surgery

K Wang, Y Du, Z Zhang, K He, Z Cheng, L Yin… - Nature Reviews …, 2023 - nature.com
Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …

Molecular engineering of AIE luminogens for NIR-II/IIb bioimaging and surgical navigation of lymph nodes

S Song, Y Wang, Y Zhao, W Huang, F Zhang, S Zhu… - Matter, 2022 - cell.com
Sentinel lymph node (SLN) imaging is vital for tumor staging and treatment decision-making,
and current methods for SLN imaging suffer from a short retention time, poor penetration …

Highly Bright Near‐Infrared Chemiluminescent Probes for Cancer Imaging and Laparotomy

X Wei, J Huang, C Zhang, C Xu, K Pu… - Angewandte …, 2023 - Wiley Online Library
Near‐infrared (NIR) chemiluminescence imaging holds potential for sensitive imaging of
cancer due to its low background; however, few NIR chemiluminophores are available …

Aggregation-induced emission luminogens for assisted cancer surgery

J Dai, H Xue, D Chen, X Lou, F Xia, S Wang - Coordination Chemistry …, 2022 - Elsevier
Surgery is still one of the most important means of treating tumors. Fluorescence imaging-
mediated surgical navigation and intraoperative phototherapy are considered to be effective …