Abstract Thioredoxins (Trxs), glutaredoxins (Grxs), and peroxiredoxins (Prxs) have been
characterized as electron donors, guards of the intracellular redox state, and “antioxidants” …

Oxidative stress is involved in the aetiology of defective embryo development. Reactive
oxygen species (ROS) may originate from embryo metabolism and/or embryo surroundings …

Oocytes and preimplantation embryos require careful regulation of the redox environment
for optimal development both in vivo and in vitro. Reactive oxygen species (ROS) are …

In brief Reactive oxygen species are generated throughout the pre-implantation period and
are necessary for normal embryo formation. However, at pathological levels, they result in …

Proper physiological function of the ovaries is very important for the entire female
reproductive system and overall health. Reactive oxygen species (ROS) are generated as …

Oxidative stress is considered causal of aging and pathological cell death, however, very
little is known about its function in the natural processes that support the formation of an …

Significance: Human apurinic/apyrimidinic endonuclease 1 (APE1, also known as REF-1)
was isolated based on its ability to cleave at AP sites in DNA or activate the DNA binding …

Supplementation of IVM medium with cysteamine, β-mercaptoethanol, cysteine and cystine
induced bovine oocyte glutathione (GSH) synthesis, but only the effect of cysteamine on the …

The DNA-binding activity of AP-1 proteins is modulated, in vitro, by a posttranslational
mechanism involving reduction oxidation. This mode of regulation has been proposed to …

The paper reviews a recent research on the role of glutathione (GSH) in the male and
female germ cells as well as during the early stages of embryo development in mammals. In …