Cholesterol reduction in cardiovascular disease—clinical benefits and possible mechanisms

GN Levine, JF Keaney Jr, JA Vita - New England Journal of …, 1995 - Mass Medical Soc
The causal role of an elevated serum cholesterol level in the genesis of atherosclerosis and
its clinical sequelae, particularly ischemic heart disease, is now well established. The …

Guar gum: a review of its pharmacological properties, and use as a dietary adjunct in hypercholesterolaemia

PA Todd, P Benfield, KL Goa - Drugs, 1990 - Springer
Synopsis Guar gum is a dietary fibre advocated for use in lowering serum total cholesterol
levels in patients with hypercholesterolaemia. Its mechanism of action is proposed to be …

Do doctors accurately assess coronary risk in their patients? Preliminary results of the coronary health assessment study

SA Grover, I Lowensteyn, KL Esrey, Y Steinert… - Bmj, 1995 - bmj.com
Objective: To evaluate the ability of doctors in primary care to assess risk patients9 risk of
coronary heart disease. Design: Questionnaire survey. Setting: Continuing medical …

The importance of triglycerides: results from the Prospective Cardiovascular Münster (PROCAM) Study

G Assmann, H Schulte - European journal of epidemiology, 1992 - Springer
In the PROCAM study hypertriglyceridaemia was much more common among men (18.6%)
than women (4.2%). Prevalence increased with age in women, but remained nearly constant …

Analytical reviews in clinical biochemistry: the quantitative analysis of cholesterol

W Richmond - Annals of clinical biochemistry, 1992 - journals.sagepub.com
Studies on the occurrence and chemical nature of cholesterol can be traced'v to the
observation, circa 1733, of the partial solubility of gallstones in alcohol! and the subsequent …

The HELP‐LDL‐apheresis multicentre study, an angiographically assessed trial on the role of LDL‐apheresis in the secondary prevention of coronary heart disease: I …

D Seidel, VW Armstrong… - European journal of …, 1991 - Wiley Online Library
Fifty‐one patients with coronary heart disease (CHD) and LDL‐cholesterol levels 200 mg dl‐
1 despite diet and drug therapy have been recruited into an angiographically controlled …

Serum lipids and lipoproteins in children, adolescents and young adults in 1980–1986

J Viikari, T Rönnemaa, A Seppänen, J Mamiemi… - Annals of …, 1991 - Taylor & Francis
A multicentre study on atherosclerosis precursors in young Finns aged three to 18 years was
started in 1980 (3596 subjects) serum lipid concentrations (cholesterol, HDL (high density …

Awareness, treatment and control of hyperlipidaemia, hypertension and diabetes mellitus in a selected population of southern Italy

A Gnasso, MC Calindro, C Carallo… - European journal of …, 1997 - Springer
The purpose of the present study was to assess the degree of awareness, treatment and
control of hyperlipidaemia compared with hypertension and diabetes mellitus in a selected …

Diet and cardiovascular disease prevention: what works?

L Van Horn, RE Kavey - Annals of Behavioral Medicine, 1997 - academic.oup.com
Diet is routinely recommended as the primary strategy for the prevention and treatment of
high blood cholesterol. The National Cholesterol Education Program (NCEP), the American …

Separation and determination of simvastatin on ZIC-HILIC stationary phases by hydrophilic interaction chromatography in pharmaceutical material products

AMM Fahad, AS Rasheed, HH Ali - Materials Today: Proceedings, 2022 - Elsevier
The hydrophilic interaction chromatography (HILIC) technique outperforms other methods in
terms of precision and sensitivity. The development and optimization of a HILIC method for …