Current treatment and recent progress in gastric cancer

SS Joshi, BD Badgwell - CA: a cancer journal for clinicians, 2021 - Wiley Online Library
Gastric cancer is not a top‐10 malignancy in the United States but represents one of the
most common causes of cancer death worldwide. Biological differences between tumors …

Microsatellite instability: a review of what the oncologist should know

K Li, H Luo, L Huang, H Luo, X Zhu - Cancer cell international, 2020 - Springer
The patients with high microsatellite instability (MSI-H)/mismatch repair deficient (dMMR)
tumors recently have been reported that can benefit from immunotherapy, and MSI can be …

Mapping the genomic diaspora of gastric cancer

KG Yeoh, P Tan - Nature reviews cancer, 2022 - nature.com
Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality.
Pioneering genomic studies, focusing largely on primary GCs, revealed driver alterations in …

Individual patient data meta-analysis of the value of microsatellite instability as a biomarker in gastric cancer

F Pietrantonio, R Miceli, A Raimondi… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE In the CLASSIC and MAGIC trials, microsatellite instability (MSI)–high status was
a favorable prognostic and potential negative predictive factor for neoadjuvant/adjuvant …

Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer: a randomized controlled trial

J Lu, CH Zheng, BB Xu, JW Xie, JB Wang, JX Lin… - 2021 - journals.lww.com
Objective: To evaluate the short-term outcomes of patients with GC who received RDG or
LDG. Summary Background Data: Despite the increasing use of RDG in patients with GC, its …

[HTML][HTML] Microsatellite instability in Gastric Cancer: Between lights and shadows

E Puliga, S Corso, F Pietrantonio, S Giordano - Cancer treatment reviews, 2021 - Elsevier
Gastric cancer (GC) represents an important contributor to the global burden of cancer,
being one of the most common and deadly malignancies worldwide. According to TCGA and …

Stromal-immune score-based gene signature: a prognosis stratification tool in gastric cancer

H Wang, X Wu, Y Chen - Frontiers in oncology, 2019 - frontiersin.org
Background: A growing amount of evidence has suggested the clinical importance of
stromal and immune cells in the gastric cancer microenvironment. However, reliable …

[HTML][HTML] PD-L1 testing in gastric cancer by the combined positive score of the 22C3 PharmDx and SP263 assay with clinically relevant cut-offs

Y Park, J Koh, HY Na, Y Kwak, KW Lee… - … : Official Journal of …, 2020 - synapse.koreamed.org
Purpose We provide a comparison between 22C3 pharmDx and SP263 assay, for
evaluating programmed death ligand 1 (PD-L1) expression in advanced gastric cancer (GC) …

Early stage gastric adenocarcinoma: clinical and molecular landscapes

Y Hirata, A Noorani, S Song, L Wang… - Nature Reviews Clinical …, 2023 - nature.com
Gastric adenocarcinoma, even when diagnosed at an early (localized) disease stage, poses
a major health-care burden with cure rates that remain unsatisfactorily low, particularly in …

Neoadjuvant and adjuvant therapy approaches to gastric cancer

C Fong, E Johnston, N Starling - Current treatment options in oncology, 2022 - Springer
Opinion statement Gastric cancer is an aggressive malignancy, requiring a multimodality
approach to achieve optimal curative rates even when the disease is amenable to surgical …