The diverse and dynamic microbial community of the human gastrointestinal tract plays a
vital role in health, with gut microbiota supporting the development and function of the gut …

Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

Microplastics (MPs) have been well demonstrated as potential threats to the ecosystem,
whereas the neurotoxicity of MPs in mammals remains to be elucidated. The current study …

SARS-CoV-2 might directly activate NLRP3 inflammasome resulting in an endogenous
adjuvant activity necessary to mount a proper adaptive immune response against the virus …

Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

Almost all human diseases are strongly associated with inflammation, and a deep
understanding of the exact mechanism is helpful for treatment. The NLRP3 inflammasome …

Inflammasomes are large intracellular multi-protein signalling complexes that are formed in
the cytosolic compartment as an inflammatory immune response to endogenous danger …

Lack of immune system cells or impairment in differentiation of immune cells is the basis for
many chronic diseases. Metabolic changes could be the root cause for this immune cell …

Immunotherapy is revolutionizing the treatment of diseases in which dysregulated immune
responses have an important role. However, most of the immunotherapy strategies currently …

Summary Background The Coronavirus Disease 2019 (COVID-19) pandemic has been a
great threat to global public health since 2020. Although the advance on vaccine …