Antivirals against the Chikungunya virus

V Battisti, E Urban, T Langer - Viruses, 2021 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has re-emerged in
recent decades, causing large-scale epidemics in many parts of the world. CHIKV infection …

Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

MS Hakim, AT Aman - Viruses, 2022 - mdpi.com
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by
the sudden onset of symptoms, including fever, rash, myalgia, and headache. In some …

Preparation and application of chikungunya pseudovirus containing double reporter genes

C Su, K Ding, J Xu, J Wu, J Liu, J Shen, H Zhou… - Scientific Reports, 2022 - nature.com
Chikungunya virus (CHIKV), a highly infectious and rapidly spread viral pathogen, is
classified as a pathogenic agent at the biosafety level 3. Operation of live authentic CHIKV …

Reactive oxygen species enhance rAAV transduction by promoting its escape from late endosomes

X Huang, X Wang, Y Ren, P Gao, W Xu, X Xie, Y Diao - Virology Journal, 2023 - Springer
Background Recent seminal studies have revealed that endosomal reactive oxygen species
(ROS) promote rather than inhibit viral infection. Some ROS generators, including shikonin …

Immune Response to Chikungunya Virus: Sex as a Biological Variable and Implications for Natural Delivery via the Mosquito

M Taylor, JO Rayner - Viruses, 2023 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-borne virus with significant public health
implications around the world. Climate change, as well as rapid urbanization, threatens to …

[HTML][HTML] Genome-wide approaches to unravel the host factors involved in Chikungunya virus replication

A Tanaka, Y Suzuki - Frontiers in Microbiology, 2022 - frontiersin.org
Chikungunya virus (CHIKV), the causative agent of Chikungunya fever (CHIKVF) that is
often characterized by fever, headache, rash, and arthralgia, is transmitted to humans by …

[PDF][PDF] CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry

ES Heinl, S Lorenz, B Schmidt, NNM Laqtom… - Iscience, 2022 - cell.com
The SARS-CoV-2 virus has triggered a worldwide pandemic. According to the BioGrid
database, CLN7 (MFSD8) is thought to interact with several viral proteins. The aim of this …

[HTML][HTML] Rlip Protein: A Potential Target for COVID-19

J Kopel, SP Singh, A Hindle, M Quirch… - Journal of Community …, 2022 - ncbi.nlm.nih.gov
Abstract On January 30, 2020, the COVID-19 epidemic was declared an international public
health emergency by the World Health Organization. Given the growing impact of the …

Pseudotyped Viruses for the Alphavirus Chikungunya Virus

J Wu, W Huang, Y Wang - Pseudotyped Viruses, 2023 - Springer
Members of the genus Alphavirus are mostly mosquito-borne pathogens that cause disease
in their vertebrate hosts. Chikungunya virus (CHIKV), which is one member of the genus …

[PDF][PDF] Journal of Community Hospital Internal Medicine Perspective s

J Kopel, SP Singh, A Hindle, M Quirch, C Bose - Perspectives - scienceopen.com
Abstract On January 30, 2020, the COVID-19 epidemic was declared an international public
health emergency by the World Health Organization. Given the growing impact of the …