Introducción La leucemia mieloblástica aguda (LMA) constituye la segunda hemopatía
maligna en la población pediátrica y una de las principales causas de mortalidad por …

Refusing treatment for potentially curable childhood cancers engenders much discussion
and debate. I present a case in which the competent parents of a young Amish child with …

Purpose Few studies have evaluated conditional survival (probability of surviving y years
given patients have already survived x years) for pediatric/adolescent patients diagnosed …

Leukemia, the most common type of cancer among children and adolescents, is a cancer of
the white blood cells. Childhood leukemia affects children's cognitive, academic, social …

Acute leukemia is the most common childhood malignancy, accounting for almost 35% of all
childhood cancers. Acute myeloid leukemia (AML) represents 15–20% of pediatric acute …

The present review summarizes the role of immunotherapy in the treatment of pediatric
acute myeloid leukemia (AML). Through the evaluation of recent clinical and pre-clinical …

Relapsed acute myeloid leukemia presenting as an isolated central nervous system myeloid
sarcoma (CNS MS) is very rare and generally entails poor outcomes. CNS MS treatment is …

Dysregulation of genes involved in the cell cycle such as TP 53, P21, P16, and PTEN plays
a key role in oncogenesis. We have earlier reported increased expression of the TP 53 …

This research was supported by the Belgian Foundation against Cancer (grant 2014–265),
FOD-KankerPlan (Actie29, grant to JP), vzw Kinderkankerfonds (grant to TL) and the …

Despite great progress in the curative treatment of acute leukemia, outcomes for those with
relapsed and/or chemotherapy-refractory disease remain poor. Current intensive cytotoxic …