A review of microbial degradation of per-and polyfluoroalkyl substances (PFAS): Biotransformation routes and enzymes

A Berhanu, I Mutanda, J Taolin, MA Qaria… - Science of the Total …, 2023 - Elsevier
Since the 1950s, copious amounts of per-and polyfluoroalkyl substances (PFAS)(dubbed
“forever chemicals”) have been dumped into the environment, causing heavy contamination …

Nothing lasts forever: understanding microbial biodegradation of polyfluorinated compounds and perfluorinated alkyl substances

LP Wackett - Microbial biotechnology, 2022 - Wiley Online Library
Poly‐and perfluorinated chemicals, including perfluorinated alkyl substances (PFAS), are
pervasive in today's society, with a negative impact on human and ecosystem health …

Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases

AN Khusnutdinova, KA Batyrova, G Brown… - The FEBS …, 2023 - Wiley Online Library
Fluorine forms the strongest single bond to carbon with the highest bond dissociation energy
among natural products. However, fluoroacetate dehalogenases (FADs) have been shown …

FluorMango, an RNA‐Based Fluorogenic Biosensor for the Direct and Specific Detection of Fluoride

C Husser, S Vuilleumier, M Ryckelynck - Small, 2023 - Wiley Online Library
Nucleic acids are not only essential actors of cell life but also extremely appealing molecular
objects in the development of synthetic molecules for biotechnological application, such as …

Enhanced removal of perfluorooctanoic acid with sequential photocatalysis and fungal treatment

MF Khan, J Paul Guin, RK Thampi, JA Sullivan… - … Science and Pollution …, 2023 - Springer
In this paper, we report the degradation of perfluorooctanoic acid (PFOA), which is a
persistent contaminant in the environment that can severely impact human health, by …

Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice

OM Ogunsuyi, PT Fasakin, OP Ajibiye, OI Ogunsuyi… - Chemosphere, 2023 - Elsevier
Perfluoroundecanoic acid (PFUnA) is an eleven carbon-chain compound that belongs to the
perfluoroalkyl carboxylic acid family. It has been detected in the human blood, effluents, and …

Environmental and dietary exposure of perfluorooctanoic acid and perfluorooctanesulfonic acid in the Nakdong River, Korea

GH Choi, DY Lee, P Bruce-Vanderpuije… - Environmental …, 2021 - Springer
This study performed the first environmental and dietary exposure assessment to explore
plant uptake of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) from …

Molecular rationale for partitioning between C–H and C–F bond activation in heme-dependent tyrosine hydroxylase

Y Wang, I Davis, I Shin, H Xu, A Liu - Journal of the American …, 2021 - ACS Publications
The heme-dependent l-tyrosine hydroxylases (TyrHs) in natural product biosynthesis
constitute a new enzyme family in contrast to the nonheme iron enzymes for DOPA …

The link between ancient microbial fluoride resistance mechanisms and bioengineering organofluorine degradation or synthesis

RB Stockbridge, LP Wackett - Nature Communications, 2024 - nature.com
Fluorinated organic chemicals, such as per-and polyfluorinated alkyl substances (PFAS)
and fluorinated pesticides, are both broadly useful and unusually long-lived. To combat …

Atlas of the microbial degradation of fluorinated pesticides

DAM Alexandrino, AP Mucha… - Critical Reviews in …, 2022 - Taylor & Francis
Fluorine-based agrochemicals have been benchmarked as the golden standard in pesticide
development, prompting their widespread use in agriculture. As a result, fluorinated …