Sex and racial differences in pharmacological response: where is the evidence? Pharmacogenetics, pharmacokinetics, and pharmacodynamics

GD Anderson - Journal of women's health, 2005 - liebertpub.com
The Food and Drug Administration (FDA) reviewed 300 new drug applications between
1995 and 2000. Of the 163 that included a sex analysis, 11 drugs showed a> 40% difference …

[HTML][HTML] Genophenotypic factors and pharmacogenomics in adverse drug reactions

R Cacabelos, V Naidoo, L Corzo, N Cacabelos… - International journal of …, 2021 - mdpi.com
Adverse drug reactions (ADRs) rank as one of the top 10 leading causes of death and
illness in developed countries. ADRs show differential features depending upon genotype …

Osteosarcoma: a surveillance, epidemiology, and end results program‐based analysis from 1975 to 2017

S Cole, DM Gianferante, B Zhu, L Mirabello - Cancer, 2022 - Wiley Online Library
Background Osteosarcoma is the most common primary bone malignancy. As a rare cancer,
population‐based studies remain small with limited information on finer demographic …

Sex and gender factors in medical studies: implications for health and clinical practice

VW Pinn - Jama, 2003 - jamanetwork.com
THE US CENSUS BUREAU PROJECTS that the US population will have increasing
numbers of women in the next decades and a greater proportion of the population will be …

Gender differences in the prescribing of antipsychotic drugs

MV Seeman - American Journal of Psychiatry, 2004 - Am Psychiatric Assoc
OBJECTIVE: The aim of this article is to offer recommendations and rationale for gender-
specific antipsychotic treatment. METHOD: The author summarizes reviews of recent …

The origins and development of psychopathology in females and males

C Zahn‐Waxler, NR Crick, EA Shirtcliff… - … : Volume one: Theory …, 2015 - Wiley Online Library
This chapter considers a range of conceptual, methodological, statistical, and substantive
issues in the study of sex differences in the development of psychopathology. It considers …

Addressing ancestry and sex bias in pharmacogenomics

M Corpas, MK Siddiqui, O Soremekun… - Annual Review of …, 2024 - annualreviews.org
The association of an individual's genetic makeup with their response to drugs is referred to
as pharmacogenomics. By understanding the relationship between genetic variants and …

Second-generation antipsychotics: is there evidence for sex differences in pharmacokinetic and adverse effect profiles?

W Aichhorn, AB Whitworth, EM Weiss, J Marksteiner - Drug safety, 2006 - Springer
Six second-generation antipsychotics (SGAs), aripiprazole, clozapine, olanzapine,
quetiapine, risperidone and ziprasidone, are currently US FDA approved. The aim of this …

[HTML][HTML] The side effect profile of Clozapine in real world data of three large mental health hospitals

E Iqbal, R Govind, A Romero, O Dzahini, M Broadbent… - PloS one, 2020 - journals.plos.org
Objective Mining the data contained within Electronic Health Records (EHRs) can potentially
generate a greater understanding of medication effects in the real world, complementing …

Lymphoma survival patterns by WHO subtype in the United States, 1973–2003

X Han, B Kilfoy, T Zheng, TR Holford, C Zhu… - Cancer causes & …, 2008 - Springer
With the incidence and prevalence of lymphoid neoplasms increasing, a comparison of
survival patterns by subtype may provide critical clues for improving the disease burden. We …