Immunotherapy has revolutionized colon cancer treatment. Immune checkpoint inhibitors
(ICIs) have shown clinical benefits for colon cancer patients, especially those with high …

While colorectal cancers (CRC) are paradigmatic tumors invaded by effector memory
lymphocytes, the mechanisms accounting for the relative resistance of MSI negative CRC to …

Simple Summary Immune Checkpoint Inhibitors (ICIs) have demonstrated clinical efficacy in
Microsatellite Instability High Colorectal Cancer (MSI-H CRC). However, in Microsatellite …

Following initial success in melanoma and lung tumours, immune checkpoint inhibitors
(ICIs) are now well recognized as a major immunotherapy treatment modality for multiple …

Simple Summary The current study identified microbial (including bacterial and viral)
diagnostic models that could discriminate colorectal tumor patients from healthy controls …

Background Treatment options are limited for participants with microsatellite stable (MSS)
metastatic colorectal cancer (mCRC) that progressed after two or more prior therapies …

The expression of programmed cell death-ligand 1 (PD-L1) is being used as a predictive
biomarker for immunotherapy in head and neck squamous cell carcinoma (HNSCC). Our …

Colorectal cancer is the third most prevalent malignancy in Western countries and a major
cause of death despite recent improvements in screening programs and early detection …

Background. Programmed cell death receptor 1 (PD‐1) and T cell immunoglobulin mucin‐3
(Tim‐3) are considered as important immunosuppressive molecules and play an important …

Background: Colorectal cancer (CRC) is considered as one of the most lethal malignancies
worldwide. However, the effective therapies remain limited. Polydatin, a main effective …