[HTML][HTML] The roles of extracellular vesicles in the immune system

EI Buzas - Nature Reviews Immunology, 2023 - nature.com
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …

[HTML][HTML] Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer

QF Han, WJ Li, KS Hu, J Gao, WL Zhai, JH Yang… - Molecular cancer, 2022 - Springer
Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …

[HTML][HTML] Dendritic cell subsets in cancer immunity and tumor antigen sensing

A Del Prete, V Salvi, A Soriani, M Laffranchi… - Cellular & molecular …, 2023 - nature.com
Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …

[HTML][HTML] Extracellular vesicles: mediators of intercellular communication in tissue injury and disease

G Berumen Sánchez, KE Bunn, HH Pua… - Cell Communication and …, 2021 - Springer
Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …

Advances in extracellular vesicle nanotechnology for precision theranostics

Q Wu, S Fu, H Xiao, J Du, F Cheng, S Wan… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …

[HTML][HTML] Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity

S Liu, W Wang, S Hu, B Jia, B Tuo, H Sun… - Cell Death & …, 2023 - nature.com
Cancer immunotherapy has transformed traditional treatments, with immune checkpoint
blockade being particularly prominent. However, immunotherapy has minimal benefit for …

[HTML][HTML] Exosomes as smart drug delivery vehicles for cancer immunotherapy

H Zhang, S Wang, M Sun, Y Cui, J Xing… - Frontiers in …, 2023 - frontiersin.org
Exosomes (Exos) as drug delivery vehicles have been widely used for cancer
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …

Curvature-sensing peptide inhibits tumour-derived exosomes for enhanced cancer immunotherapy

S Shin, H Ko, CH Kim, BK Yoon, S Son, JA Lee… - Nature Materials, 2023 - nature.com
Tumour-derived exosomes (T-EXOs) impede immune checkpoint blockade therapies,
motivating pharmacological efforts to inhibit them. Inspired by how antiviral curvature …

Extracellular vesicles as next generation immunotherapeutics

DW Greening, R Xu, A Ale, CE Hagemeyer… - Seminars in Cancer …, 2023 - Elsevier
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …

CD73 in small extracellular vesicles derived from HNSCC defines tumour‐associated immunosuppression mediated by macrophages in the microenvironment

T Lu, Z Zhang, J Zhang, X Pan, X Zhu… - Journal of …, 2022 - Wiley Online Library
Research on tumour cell‐derived small extracellular vesicles (sEVs) that regulate tumour
microenvironment (TME) has provided strategies for targeted therapy of head and neck …