Invasive candidiasis

C Lass-Flörl, SS Kanj, NP Govender… - Nature Reviews …, 2024 - nature.com
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

[HTML][HTML] Design of a lipid nano-delivery system containing recombinant Candida albicans chitinase 3 as a potential vaccine against fungal infections

A Costa-Barbosa, MI Pacheco, C Carneiro… - Biomedicine & …, 2023 - Elsevier
Opportunistic fungi cause lethal systemic infections and impose high medical costs to health
systems. The World Health Organization has recognized the importance of fungal infections …

RAD51–WSS1-dependent genetic pathways are essential for DNA–protein crosslink repair and pathogenesis in Candida albicans

P Kumari, SR Sahu, BG Utkalaja, A Dutta… - Journal of Biological …, 2023 - ASBMB
Genetic analyses in Saccharomyces cerevisiae suggest that nucleotide excision repair
(NER), homologous recombination (HR), and protease-dependent repair pathways …

Pol32, an accessory subunit of DNA polymerase delta, plays an essential role in genome stability and pathogenesis of Candida albicans

SK Patel, SR Sahu, BG Utkalaja, S Bose… - Gut Microbes, 2023 - Taylor & Francis
Candida albicans is a pathobiont that inflicts serious bloodstream fungal infections in
individuals with compromised immunity and gut dysbiosis. Genomic diversity in the form of …

Advancing Vaccine Strategies against Candida Infections: Exploring New Frontiers

G Kaur, S Chawla, P Kumar, R Singh - Vaccines, 2023 - mdpi.com
Candida albicans, along with several non-albicans Candida species, comprise a prominent
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …

Escherichia coli, but Not Staphylococcus aureus, Functions as a Chelating Agent That Exhibits Antifungal Activity against the Pathogenic Yeast Candida albicans

S Bose, DV Singh, TK Adhya, N Acharya - Journal of Fungi, 2023 - mdpi.com
Humans are colonized by diverse populations of microbes. Infections by Candida albicans,
an opportunistic fungal pathogen, are a result of imbalances in the gut microbial ecosystem …

Features of the rare pathogen Meyerozyma guilliermondii strain SO and comprehensive in silico analyses of its adherence-contributing virulence factor agglutinin …

SJ Lim, ND Muhd Noor, S Sabri… - Journal of …, 2023 - Taylor & Francis
Meyerozyma guilliermondii is a rare yeast pathogen contributing to the deadly invasive
candidiasis. M. guilliermondii strain SO, as a promising protein expression host, showed …

Hsp90-Mediated Multi-Drug Resistance in DNA Polymerase-Defective Strains of Candida albicans

BG Utkalaja, SR Sahu, SS Parida, N Acharya - Journal of Fungi, 2024 - mdpi.com
The incidence of infections caused by Candida species, specifically by drug-resistant
isolates, is a major health concern as they can disseminate to and colonize most vital …

Molecular Cloning, Heterologous Expression, Purification, and Evaluation of Protein–Ligand Interactions of CYP51 of Candida krusei Azole-Resistant Fungal Strain

TV Tsybruk, LA Kaluzhskiy, YV Mezentsev… - Biomedicines, 2023 - mdpi.com
Due to the increasing prevalence of fungal diseases caused by fungi of the genus Candida
and the development of pathogen resistance to available drugs, the need to find new …

Pathophysiological microenvironments in oral candidiasis

MR Jørgensen - APMIS, 2024 - Wiley Online Library
Oral candidiasis (OC), a prevalent opportunistic infection of the oral mucosa, presents a
considerable health challenge, particularly in individuals with compromised immune …