Vascular calcification in chronic kidney disease: diversity in the vessel wall

P Dube, A DeRiso, M Patel, D Battepati… - Biomedicines, 2021 - mdpi.com
Vascular calcification (VC) is one of the major causes of cardiovascular morbidity and
mortality in patients with chronic kidney disease (CKD). VC is a complex process expressing …

State of the art review: brachial-ankle PWV

H Tomiyama, K Shiina - Journal of atherosclerosis and thrombosis, 2020 - jstage.jst.go.jp
First, we would like to briefly describe the changes in the arterial medial layer that occur in
association with atherosclerotic vascular damage, affecting the arterial stiffness5-8). The …

Unspliced XBP1 counteracts β-catenin to inhibit vascular calcification

L Yang, R Dai, H Wu, Z Cai, N Xie, X Zhang… - Circulation …, 2022 - Am Heart Assoc
Background: Vascular calcification is a prevalent complication in chronic kidney disease and
contributes to increased cardiovascular morbidity and mortality. XBP1 (X-box binding protein …

The controversy of klotho as a potential biomarker in chronic kidney disease

LX Yu, SS Li, MY Sha, JW Kong, JM Ye… - Frontiers in …, 2022 - frontiersin.org
Klotho is an identified longevity gene with beneficial pleiotropic effects on the kidney.
Evidence shows that a decline in serum Klotho level occurs in early chronic kidney disease …

Arterial stiffness determinants for primary cardiovascular prevention among healthy participants

A Vallée - Journal of clinical medicine, 2022 - mdpi.com
Background: Arterial stiffness (AS), measured by arterial stiffness index (ASI), can be
considered as a major denominator in cardiovascular (CV) diseases. Thus, it remains …

The relationship of endothelial function and arterial stiffness with subclinical target organ damage in essential hypertension

Y Sun, F Liu, Y Zhang, Y Lu, Z Su, H Ji… - The Journal of …, 2022 - Wiley Online Library
This study aimed to explore whether brachial‐ankle pulse wave velocity (baPWV) and
brachial artery flow‐mediated dilation (FMD) or the interaction of both parameters are …

Hydrogen sulfide prevents arterial medial calcification in rats with diabetic nephropathy

FZ Wang, H Zhou, HY Wang, HB Dai, Q Gao… - BMC Cardiovascular …, 2021 - Springer
Background Arterial medial calcification (AMC) is associated with a high incidence of
cardiovascular risk in patients with type 2 diabetes and chronic kidney disease. Here, we …

Gender-related differences in chronic kidney disease-associated vascular calcification risk and potential risk mediators: a scoping review

PY Wu, SY Lee, KV Chang, CT Chao, JW Huang - Healthcare, 2021 - mdpi.com
Vascular calcification (VC) involves the deposition of calcium apatite in vascular intima or
media. Individuals of advanced age, having diabetes mellitus or chronic kidney disease …

Dirty jobs: macrophages at the heart of cardiovascular disease

TW Stevens, FK Khalaf, S Soehnlen, P Hegde, K Storm… - Biomedicines, 2022 - mdpi.com
Cardiovascular disease (CVD) is one of the greatest public health concerns and is the
leading cause of morbidity and mortality in the United States and worldwide. CVD is a broad …

Effect of lanthanum carbonate on serum calciprotein particles in patients with stage 3–4 CKD—results from a placebo-controlled randomized trial

MK Tiong, ER Smith, EM Pascoe… - Nephrology Dialysis …, 2023 - academic.oup.com
Background Calciprotein particles (CPP) are colloidal aggregates of calcium phosphate and
the mineral-binding protein fetuin-A, and are potential mediators of cardiovascular disease …