Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Apelin is an endogenous peptide identified as a ligand of the G protein-coupled receptor
APJ. Apelin belongs to the family of adipokines, which are bioactive mediators released by …

Immune cells are present in normal breast tissue and in breast carcinoma. The nature and
distribution of the immune cell subtypes in these tissues are reviewed to promote a better …

The review aims to comprehensively present the impact of exposure to endocrine disruptors
(EDs) in relation to the clinical manifestation of obesity and related diseases, including …

The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …

Research on obesity-and diabetes mellitus (DM)-related carcinogenesis has expanded
exponentially since these two diseases were recognized as important risk factors for …

Obesity is often linked to malignancies including multiple myeloma, and the underlying
mechanisms remain elusive. Here we showed that acetyl-CoA synthetase 2 (ACSS2) may …

Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …

The long-term effect of therapeutic diets in obesity treatment is a challenge at present. The
current study aimed to evaluate the long-term effect of a very low-calorie-ketogenic (VLCK) …

Abstract Purpose of Review Adipocytes have adapted to store energy in the form of lipid and
also secrete circulating factors called adipokines that signal to other tissues to coordinate …