[HTML][HTML] The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE
RJ Guerreiro, DR Gustafson, J Hardy - Neurobiology of aging, 2012 - Elsevier
Alzheimer's disease (AD) is a complex disorder with a clear genetic component. Three
genes have been identified as the cause of early onset familial AD (EOAD). The most …
genes have been identified as the cause of early onset familial AD (EOAD). The most …
Trajectories of cognitive decline in Alzheimer's disease
PA Wilkosz, HJ Seltman, B Devlin… - International …, 2010 - cambridge.org
Background: Late-onset Alzheimer disease (LOAD) is a clinically heterogeneous complex
disease defined by progressively disabling cognitive impairment. Psychotic symptoms which …
disease defined by progressively disabling cognitive impairment. Psychotic symptoms which …
Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders
P Penzes, A Buonanno, M Passafaro… - Journal of …, 2013 - Wiley Online Library
Psychiatric and neurodegenerative disorders, including intellectual disability, autism
spectrum disorders (ASD), schizophrenia (SZ), and Alzheimer's disease, pose an immense …
spectrum disorders (ASD), schizophrenia (SZ), and Alzheimer's disease, pose an immense …
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
MAA DeMichele-Sweet, L Klei, B Creese… - Molecular …, 2021 - nature.com
Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent
in Alzheimer disease (AD with psychosis, AD+ P). AD+ P affects~ 50% of individuals with …
in Alzheimer disease (AD with psychosis, AD+ P). AD+ P affects~ 50% of individuals with …
The role of D-amino acids in Alzheimer's disease
L Piubelli, G Murtas, V Rabattoni… - Journal of Alzheimer's …, 2021 - content.iospress.com
Abstract Alzheimer's disease (AD), the main cause of dementia worldwide, is characterized
by a complex and multifactorial etiology. In large part, excitatory neurotransmission in the …
by a complex and multifactorial etiology. In large part, excitatory neurotransmission in the …
Genome-wide association study of Alzheimer's disease with psychotic symptoms
Psychotic symptoms occur in∼ 40% of subjects with Alzheimer's disease (AD) and are
associated with more rapid cognitive decline and increased functional deficits. They show …
associated with more rapid cognitive decline and increased functional deficits. They show …
Revisiting criteria for psychosis in Alzheimer's disease and related dementias: toward better phenotypic classification and biomarker research
Background: Psychotic symptoms are common in Alzheimer's disease (AD) and related
neurodegenerative disorders and are associated with more rapid disease progression and …
neurodegenerative disorders and are associated with more rapid disease progression and …
Alzheimer's disease genetics: current knowledge and future challenges
Alzheimer's disease (AD) is highly heritable, but genetically complex. Recently, three large‐
scale genome‐wide association studies have made substantial breakthroughs in …
scale genome‐wide association studies have made substantial breakthroughs in …
Genetic risk for schizophrenia and psychosis in Alzheimer disease
MAA DeMichele-Sweet, EA Weamer, L Klei… - Molecular …, 2018 - nature.com
Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent
in Alzheimer disease (AD), affecting~ 40 to 60% of individuals with AD (AD with psychosis …
in Alzheimer disease (AD), affecting~ 40 to 60% of individuals with AD (AD with psychosis …