Despite the widespread use of antineoplastic platinum drugs, a number of accompanying
disadvantages exist. In connection with attempts to circumvent these problems new platinum …

The importance of platinum drugs in cancer chemotherapy is underscored by the clinical
success of cisplatin [cis-diamminedichloroplatinum (II)] and its analogues and by clinical …

Platinum‐based compounds are widely used as chemotherapeutics for the treatment of a
variety of cancers. The anticancer activity of cisplatin and other platinum drugs is believed to …

Two cobalt (III) Schiff base complexes, trans-[Co (salen)(DA) 2](ClO4)(1) and trans-[Co
(salophen)(DA) 2](ClO4)(2)(where salen: N, N'-bis (salicylidene) ethylenediamine, salopen …

To explore the therapeutic potential of copper-based benzimidazole complexes, tetranuclear
Cu (II) complex 1 and dinuclear ternary amino acid complexes 2 and 3 {L-trp and L-val …

Despite the synthesis of hundreds of new platinum (II) and platinum (IV)-based complexes
each year as potential anticancer drugs, only three have received world-wide approval …

Since the introduction of cisplatin to oncology in 1978, Pt (II) and Pd (II) compounds have
been intensively studied with a view to develop the improved anticancer agents. Polynuclear …

The initial report of the therapeutic anticancer properties of a di-nuclear platinum complex in
1988 started a new paradigm in platinum based chemotherapy. Several multi-nuclear …

The interaction of native calf thymus DNA with clodinafop-propargyl (CP), in 10 mM HEPES
aqueous solutions at neutral pH 7.2, has been investigated by spectrophotometric, circular …

The Pt (II) complex, PtCl2 (DIP)(DIP= chelating dinitrogen ligand: 4, 7‐diphenyl‐1, 10‐
phenanthroline), was synthesized and characterized by elemental analysis (CHN) and 1H …