Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits
The genus Cinnamomum includes a number of plant species largely used as food, food
additives and spices for a long time. Different traditional healing systems have used these …
additives and spices for a long time. Different traditional healing systems have used these …
Class II PI3K functions in cell biology and disease
The phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases that phosphorylate
inositol phospholipids, thereby controlling membrane lipid composition and regulating a …
inositol phospholipids, thereby controlling membrane lipid composition and regulating a …
The diverse functions of IMP2/IGF2BP2 in metabolism
N Dai - Trends in Endocrinology & Metabolism, 2020 - cell.com
The human insulin-like growth factor 2 (IGF2) mRNA binding protein family (IMPs/IGF2BPs)
is involved in a spectrum of biological processes, including development, tumorigenesis …
is involved in a spectrum of biological processes, including development, tumorigenesis …
Mechanisms underlying the comorbidity of schizophrenia and type 2 diabetes mellitus
Y Mizuki, S Sakamoto, Y Okahisa… - International Journal …, 2021 - academic.oup.com
The mortality rate of patients with schizophrenia is high, and life expectancy is shorter by 10
to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among …
to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among …
[HTML][HTML] RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression
Abstract Background Type 2 diabetes (T2D) is a common metabolic disease. Variants in
human IGF2 mRNA binding protein 2 (IMP2/IGF2BP2) are associated with increased risk of …
human IGF2 mRNA binding protein 2 (IMP2/IGF2BP2) are associated with increased risk of …
The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward
FK Ndiaye, M Huyvaert, A Ortalli, M Canouil… - International journal of …, 2020 - nature.com
Background Genome-wide association studies (GWAS) have identified more than 250 loci
associated with body mass index (BMI) and obesity. However, post-GWAS functional …
associated with body mass index (BMI) and obesity. However, post-GWAS functional …
Nutrient sensing, signaling and ageing: the role of IGF-1 and mTOR in ageing and age-related disease
SC Johnson - Biochemistry and Cell Biology of Ageing: Part I …, 2018 - Springer
Nutrient signaling through insulin/IGF-1 was the first pathway demonstrated to regulate
ageing and age-related disease in model organisms. Pharmacological or dietary …
ageing and age-related disease in model organisms. Pharmacological or dietary …
Class II PI3Ks at the intersection between signal transduction and membrane trafficking
Phosphorylation of inositol phospholipids by the family of phosphoinositide 3-kinases
(PI3Ks) is crucial in controlling membrane lipid composition and regulating a wide range of …
(PI3Ks) is crucial in controlling membrane lipid composition and regulating a wide range of …
[HTML][HTML] Genes whose gain or loss-of-function increases skeletal muscle mass in mice: A systematic literature review
SAJ Verbrugge, M Schönfelder, L Becker… - Frontiers in …, 2018 - frontiersin.org
Skeletal muscle mass differs greatly in mice and humans and this is partially inherited. To
identify muscle hypertrophy candidate genes we conducted a systematic review to identify …
identify muscle hypertrophy candidate genes we conducted a systematic review to identify …
Interaction of BDNF rs6265 variants and energy and protein intake in the risk for glucose intolerance and type 2 diabetes in middle-aged adults
JW Daily, S Park - Nutrition, 2017 - Elsevier
Objectives Brain-derived neurotrophic factor (BDNF) is associated with the risk for
Alzheimer's disease and type 2 diabetes. The aim of this study was to examine the …
Alzheimer's disease and type 2 diabetes. The aim of this study was to examine the …