Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …

Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …

Almost all human diseases are strongly associated with inflammation, and a deep
understanding of the exact mechanism is helpful for treatment. The NLRP3 inflammasome …

Staphylococcus aureus is a formidable pathogen capable of causing infections in different
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …

Inflammasomes are multi-protein signaling complexes that trigger the activation of
inflammatory caspases and the maturation of interleukin-1β. Among various inflammasome …

Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …

Inflammasome signalling is an emerging pillar of innate immunity and has a central role in
the regulation of gastrointestinal health and disease. Activation of the inflammasome …

Staphylococcus aureus is a major bacterial pathogen that causes disease worldwide. The
emergence of strains that are resistant to commonly used antibiotics and the failure of …

The activator and composition of the NLRP6 inflammasome remain poorly understood. We
find that lipoteichoic acid (LTA), a molecule produced by Gram-positive bacteria, binds and …