Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Dynamic PET (dPET) studies have been used until now primarily within research purposes.
Although it is generally accepted that the information provided by dPET is superior to that of …

Development of new oncology drugs has increased since the improved understanding of
cancer's complex biology. The oncology field has become the top therapeutic research area …

Introduction: Epidermal growth factor receptor (EGFR) mutated NSCLC is best treated using
an EGFR tyrosine kinase inhibitor (TKI). The presence and accessibility of EGFR …

PET/CT with the tracer 2-[18 F] fluoro-2-deoxy-D-glucose ([18 F] FDG) has improved
diagnostic imaging in cancer and is routinely used for diagnosing, staging and treatment …

Multiple small molecule PET tracers have been developed for the imaging of the epidermal
growth factor receptor (EGFR). These tracers target the tyrosine kinase (TK) domain of the …

Precision medicine is playing a pivotal role in strategies of cancer therapy. Unlike
conventional one-size-fits-all chemotherapy or radiotherapy modalities, precision medicine …

Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate
and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is …

Non-small cell lung cancer (NSCLC) therapy has entered a rapidly advancing era of
precision medicine with an ever increasing number of drugs directed against a variety of …