[HTML][HTML] Obesity, inflammation, and immune system in osteoarthritis
U Nedunchezhiyan, I Varughese, ARJ Sun… - Frontiers in …, 2022 - frontiersin.org
Obesity remains the most important risk factor for the incidence and progression of
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …
Inflammaging and osteoarthritis
Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …
worldwide. While in the past it was considered a mere consequence of cartilage degradation …
[HTML][HTML] Knee osteoarthritis: epidemiology, pathogenesis, and mesenchymal stem cells: what else is new? An update
R Giorgino, D Albano, S Fusco, GM Peretti… - International journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …
[HTML][HTML] The immune microenvironment in cartilage injury and repair
M Li, H Yin, Z Yan, H Li, J Wu, Y Wang, F Wei, G Tian… - Acta Biomaterialia, 2022 - Elsevier
The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …
[HTML][HTML] Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
[HTML][HTML] NF-κB signaling pathways in osteoarthritic cartilage destruction
MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
[HTML][HTML] Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis
We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the
most widespread arthritis in the world, using the powerful tool of single-cell RNA …
most widespread arthritis in the world, using the powerful tool of single-cell RNA …
Progress of microfluidic hydrogel‐based scaffolds and organ‐on‐chips for the cartilage tissue engineering
Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …
the globe. Numerous approaches have been employed to treat cartilage diseases …
[HTML][HTML] Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis
The presence or absence of anti-citrullinated peptide antibodies (ACPA) and associated
disparities in patients with rheumatoid arthritis (RA) implies disease heterogeneity with …
disparities in patients with rheumatoid arthritis (RA) implies disease heterogeneity with …
[HTML][HTML] Synovitis in osteoarthritis: current understanding with therapeutic implications
A Mathiessen, PG Conaghan - Arthritis research & therapy, 2017 - Springer
Modern concepts of osteoarthritis (OA) have been forever changed by modern imaging
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …