[HTML][HTML] Non-alkaloid cholinesterase inhibitory compounds from natural sources

AN Tamfu, S Kucukaydin, B Yeskaliyeva, M Ozturk… - Molecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a severe neurodegenerative disorder of different brain regions
accompanied by distresses and affecting more than 25 million people in the world. This …

Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/TLR4/NF-κB pathways in BV2 cells

J Zhang, Y Zheng, Y Luo, Y Du, X Zhang, J Fu - Molecular immunology, 2019 - Elsevier
Highlights•Curcumin reversed LPS-induced decrease in BV2 cell viability and
morphological changes.•Curcumin promoted microglial polarization from the M1 to the M2 …

Insulin mediated novel therapies for the treatment of Alzheimer's disease

SK Dubey, KK Lakshmi, KV Krishna, M Agrawal… - Life sciences, 2020 - Elsevier
Alzheimer's disease, a progressive neurodegenerative disorder, is one of the leading
causes of death in the USA, along with cancer and cardiac disorders. AD is characterized by …

[HTML][HTML] Anticancer plant-derivatives: Deciphering their oncopreventive and therapeutic potential in molecular terms

R Gahtori, AH Tripathi, A Kumari, N Negi… - Future Journal of …, 2023 - Springer
Background Over the years, phytomedicines have been widely used as natural modalities
for the treatment and prevention of various diseases by different ethnic groups across the …

[HTML][HTML] Anti-neuroinflammatory potential of natural products in the treatment of Alzheimer's disease

M Deng, W Yan, Z Gu, Y Li, L Chen, B He - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD) is an age-related chronic progressive neurodegenerative disease,
which is the main cause of dementia in the elderly. Much evidence shows that the onset and …

[HTML][HTML] Baicalin and geniposide inhibit polarization and inflammatory injury of OGD/R-treated microglia by suppressing the 5-LOX/LTB4 pathway

HM Li, Y Wang, B Wang, M Li, JP Liu, HL Yang… - Neurochemical …, 2021 - Springer
Cerebral ischemia causes severe neurological disorders and neuronal dysfunction. Baicalin
(BC), geniposide (GP), and their combination (BC/GP) have been shown to inhibit post …

Evaluating Cannabis sativa L.'s neuroprotection potential: From bench to bedside

JS Laws III, SD Smid - Phytomedicine, 2022 - Elsevier
Background Neurodegenerative diseases and dementia pose a global health challenge in
an aging population, exemplified by the increasing incidence and prevalence of its most …

[HTML][HTML] Neurotrophic effects of intermittent fasting, calorie restriction and exercise: a review and annotated bibliography

E Mayor - Frontiers in Aging, 2023 - frontiersin.org
In the last decades, important progress has been achieved in the understanding of the
neurotrophic effects of intermittent fasting (IF), calorie restriction (CR) and exercise …

[HTML][HTML] Phytochemicals targeting oxidative stress, interconnected neuroinflammatory, and neuroapoptotic pathways following radiation

S Fakhri, S Piri, SZ Moradi, H Khan - Current Neuropharmacology, 2022 - ncbi.nlm.nih.gov
The radiation for therapeutic purposes has shown positive effects in different contexts;
however, it can increase the risk of many age-related and neurodegenerative diseases such …

[HTML][HTML] Promising intervention approaches to potentially resolve neuroinflammation and steroid hormones alterations in Alzheimer's disease and its neuropsychiatric …

C Scassellati, AC Galoforo, C Esposito, M Ciani… - Aging and …, 2021 - ncbi.nlm.nih.gov
Neuroinflammation is a biological process by which the central nervous system responds to
stimuli/injuries affecting its homeostasis. So far as this reactive response becomes …