Stochastic simulation uncertainty analysis to accelerate flexible biomanufacturing process development

W Xie, RR Barton, BL Nelson, K Wang - European Journal of Operational …, 2023 - Elsevier
Motivated by critical challenges and needs from biopharmaceuticals manufacturing, we
propose a general metamodel-assisted stochastic simulation uncertainty analysis framework …

Statistically Optimal Uncertainty Quantification for Expensive Black-Box Models

S He, H Lam - arXiv preprint arXiv:2408.05887, 2024 - arxiv.org
Uncertainty quantification, by means of confidence interval (CI) construction, has been a
fundamental problem in statistics and also important in risk-aware decision-making. In this …

Fixed Budget Ranking and Selection with Streaming Input Data

Y Wang, E Zhou - 2022 Winter Simulation Conference (WSC), 2022 - ieeexplore.ieee.org
We consider a fixed budget ranking and selection problem with input uncertainty, where
unknown input distributions can be estimated using input data arriving in batches of varying …

Quantifying Distributional Input Uncertainty via Inflated Kolmogorov-Smirnov Confidence Band

M Chen, H Lam, Z Liu - arXiv preprint arXiv:2403.09877, 2024 - arxiv.org
In stochastic simulation, input uncertainty refers to the propagation of the statistical noise in
calibrating input models to impact output accuracy, in addition to the Monte Carlo simulation …

Doubly robust stein-kernelized monte carlo estimator: Simultaneous bias-variance reduction and supercanonical convergence

H Lam, H Zhang - Journal of Machine Learning Research, 2023 - jmlr.org
Standard Monte Carlo computation is widely known to exhibit a canonical square-root
convergence speed in terms of sample size. Two recent techniques, one based on control …

Distributional input uncertainty

M Chen, Z Liu, H Lam - 2022 Winter Simulation Conference …, 2022 - ieeexplore.ieee.org
The vast majority of the simulation input uncertainty literature focuses on estimating target
output quantities that are real-valued. However, outputs of simulation models are random …

Propagation of Input Tail Uncertainty in Rare-Event Estimation: A Light versus Heavy Tail Dichotomy

Z Huang, H Lam, Z Liu - arXiv preprint arXiv:2401.00172, 2023 - arxiv.org
We consider the estimation of small probabilities or other risk quantities associated with rare
but catastrophic events. In the model-based literature, much of the focus has been devoted …

Blackbox Simulation Optimization

H Cao, JQ Hu, T Lian - Journal of the Operations Research Society of …, 2024 - Springer
Simulation optimization is a widely used tool in the analysis and optimization of complex
stochastic systems. The majority of the previous works on simulation optimization rely …

Efficient Input Uncertainty Quantification for Ratio Estimator

L He, B Feng, E Song - arXiv preprint arXiv:2410.04696, 2024 - arxiv.org
We study the construction of a confidence interval (CI) for a simulation output performance
measure that accounts for input uncertainty when the input models are estimated from finite …

[引用][C] Portfolio management of a small RES utility with a structural vector autoregressive model of electricity markets in Germany

K Maciejowska - Operations Research and …, 2022 - Oficyna Wydawnicza Politechniki …