Post-cardiac arrest: mechanisms, management, and future perspectives

T Lazzarin, CR Tonon, D Martins, EL Fávero Jr… - Journal of Clinical …, 2022 - mdpi.com
Cardiac arrest is an important public health issue, with a survival rate of approximately 15 to
22%. A great proportion of these deaths occur after resuscitation due to post-cardiac arrest …

Pharmacologic neuroprotection in ischemic brain injury after cardiac arrest

A Katz, SB Brosnahan, J Papadopoulos… - Annals of the New …, 2022 - Wiley Online Library
Cardiac arrest has many implications for morbidity and mortality. Few interventions have
been shown to improve return of spontaneous circulation (ROSC) and long‐term outcomes …

Cytokine hemoadsorption with CytoSorb® in post-cardiac arrest syndrome, a pilot randomized controlled trial

C Monard, N Bianchi, E Poli, M Altarelli… - Critical Care, 2023 - Springer
Background Hemoadsorption (HA) might mitigate the systemic inflammatory response
associated with post-cardiac arrest syndrome (PCAS) and improve outcomes. Here, we …

Bio-physiological susceptibility of the brain, heart, and lungs to systemic ischemia reperfusion and hyperoxia-induced injury in post-cardiac arrest rats

T Aoki, V Wong, Y Endo, K Hayashida, R Takegawa… - Scientific Reports, 2023 - nature.com
Cardiac arrest (CA) patients suffer from systemic ischemia–reperfusion (IR) injury leading to
multiple organ failure; however, few studies have focused on tissue-specific …

The association between heart diseases and suicide: a nationwide cohort study

BD Petersen, E Stenager… - Journal of internal …, 2020 - Wiley Online Library
Objective To assess the association between specific heart diseases and suicide. Design
Nationwide retrospective cohort study. Participants A total of 7 298 002 individuals (3 640 …

[HTML][HTML] Controlled automated reperfusion of the whole body after cardiac arrest

G Trummer, C Benk, F Beyersdorf - Journal of Thoracic Disease, 2019 - ncbi.nlm.nih.gov
Background Sudden circulatory arrest (CA) requiring cardiopulmonary resuscitation (CPR)
has for decades been associated with high mortality and frequent neurological sequelae in …

[PDF][PDF] 神经血管单位在心脏骤停后脑损伤中发挥的关键作用

许双, 麻艳楠, 刘茜, 顾路路, 周思仪, 李贝贝… - 临床急诊杂志, 2023 - lcjz.whuhzzs.com
目前心脏骤停后脑损伤(post-cardiacarrestbraininjury, PCABI) 的病理生理机制研究尚不透彻,
导致PCABI 相关的治疗效果欠佳. 神经血管单位(neurovascularunit, NVU) …

High inflammatory burden: a potential cause of myocardial injury in critically ill patients with COVID-19

Y Song, P Gao, T Ran, H Qian, F Guo… - Frontiers in …, 2020 - frontiersin.org
Background: Myocardial injury is a severe complication of novel coronavirus disease
(COVID-19), and inflammation has been suggested as a potential cause of myocardial …

Non-invasive pulsatile shear stress modifies endothelial activation; a narrative review

JA Adams, A Uryash, JR Lopez - Biomedicines, 2022 - mdpi.com
The monolayer of cells that line both the heart and the entire vasculature is the endothelial
cell (EC). These cells respond to external and internal signals, producing a wide array of …

Cardiac arrest induced by asphyxia versus ventricular fibrillation elicits comparable early changes in cytokine levels in the rat brain, heart, and serum

T Uray, C Dezfulian, AA Palmer, KM Miner… - Journal of the …, 2021 - Am Heart Assoc
Background Current postresuscitative care after cardiac arrest (CA) does not address the
cause of CA. We previously reported that asphyxial CA (ACA) and ventricular fibrillation CA …