Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity
P Eric, E Willert, J Kim, J Higgins - 2015 - Google Patents
the present invention relates to methods of screening molecular libraries in order to identify
cytotoxic recombinant polypeptides, each polypeptide comprising a target binding region …
cytotoxic recombinant polypeptides, each polypeptide comprising a target binding region …
Cell-targeting molecules comprising de-immunized, Shiga toxin a subunit effectors and CD8+ t-cell epitopes
P Eric, E Willert, S Rajagopalan, GL Robinson… - US Patent …, 2022 - Google Patents
2021-05-11 Assigned to MOLECULAR TEMPLATES, INC. reassignment MOLECULAR
TEMPLATES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
TEMPLATES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
De-immunized, Shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
P Eric, E Willert, GL Robinson, S Rajagopalan… - US Patent …, 2022 - Google Patents
The present invention relates to Shiga toxin A Subunit derived polypeptides and cell-
targeting molecules comprising amino acid substitutions which equip the polypeptides with …
targeting molecules comprising amino acid substitutions which equip the polypeptides with …
Shiga toxin a subunit effector polypeptides, Shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
P Eric, E Willert - US Patent 11,389,542, 2022 - Google Patents
The present invention provides Shiga toxin A Subunit derived polypeptides, scaffolds, and
cell-targeting molecules comprising amino acid substitutions which equip the molecules with …
cell-targeting molecules comprising amino acid substitutions which equip the molecules with …
MHC class I epitope delivering polypeptides
P Eric, E Willert - US Patent 11,312,751, 2022 - Google Patents
The present invention is directed to T-cell epitope delivering polypeptides which deliver one
or more CD8+ T-cell epitopes to the MHC class I presentation pathway of a cell, including …
or more CD8+ T-cell epitopes to the MHC class I presentation pathway of a cell, including …
Shiga toxin A subunit effector polypeptides, Shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
P Eric, E Willert - US Patent 11,857,628, 2024 - Google Patents
US11857628B2 - Shiga toxin A subunit effector polypeptides, Shiga toxin effector scaffolds, and
cell-targeting molecules for site-specific conjugation - Google Patents US11857628B2 - Shiga …
cell-targeting molecules for site-specific conjugation - Google Patents US11857628B2 - Shiga …