[HTML][HTML] Causes and consequences of snake venom variation

NR Casewell, TNW Jackson, AH Laustsen… - Trends in …, 2020 - cell.com
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …

[HTML][HTML] Snakebite envenoming

JM Gutiérrez, JJ Calvete, AG Habib… - Nature reviews Disease …, 2017 - nature.com
Snakebite envenoming is a neglected tropical disease that kills> 100,000 people and
maims> 400,000 people every year. Impoverished populations living in the rural tropics are …

[HTML][HTML] The chemistry of snake venom and its medicinal potential

AL Oliveira, MF Viegas, SL da Silva… - Nature Reviews …, 2022 - nature.com
The fascination and fear of snakes dates back to time immemorial, with the first scientific
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …

[HTML][HTML] The diversity of venom: the importance of behavior and venom system morphology in understanding its ecology and evolution

V Schendel, LD Rash, RA Jenner, EAB Undheim - Toxins, 2019 - mdpi.com
Venoms are one of the most convergent of animal traits known, and encompass a much
greater taxonomic and functional diversity than is commonly appreciated. This knowledge …

[HTML][HTML] Multifunctional toxins in snake venoms and therapeutic implications: From pain to hemorrhage and necrosis

CR Ferraz, A Arrahman, C Xie, NR Casewell… - Frontiers in ecology …, 2019 - frontiersin.org
Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …

Constraining cyclic peptides to mimic protein structure motifs

TA Hill, NE Shepherd, F Diness… - Angewandte Chemie …, 2014 - Wiley Online Library
Many proteins exert their biological activities through small exposed surface regions called
epitopes that are folded peptides of well‐defined three‐dimensional structures. Short …

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

FJ Vonk, NR Casewell, CV Henkel… - Proceedings of the …, 2013 - National Acad Sciences
Snakes are limbless predators, and many species use venom to help overpower relatively
large, agile prey. Snake venoms are complex protein mixtures encoded by several …

[HTML][HTML] Bee venom: From venom to drug

A Khalil, BH Elesawy, TM Ali, OM Ahmed - Molecules, 2021 - mdpi.com
Insects of the order Hymenoptera have a defensive substance that contains many
biologically active compounds. Specifically, venom from honeybees (Apis mellifera) contains …

Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise

J Slagboom, J Kool, RA Harrison… - British journal of …, 2017 - Wiley Online Library
Snake venoms are mixtures of numerous proteinacious components that exert diverse
functional activities on a variety of physiological targets. Because the toxic constituents …

The biology and evolution of spider venoms

T Lüddecke, V Herzig, BM Von Reumont… - Biological …, 2022 - Wiley Online Library
Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million
years. They are well known for their complex venom systems that are used to overpower …