In the setting of viral challenge, natural killer (NK) cells play an important role as an early
immune responder against infection. During this response, significant changes in the NK cell …

Purpose: Head and neck squamous cell carcinoma (HNSCC) is an aggressive tumor with
low response rates to frontline PD-1 blockade. Natural killer (NK) cells are a promising …

Background The natural killer (NK) complex (NKC) harbors multiple genes such as KLRC1
(encoding NKG2A) and KLRK1 (encoding NKG2D) that are central to regulation of NK cell …

Acute Myeloid Leukemia (AML) is a complex disease with rapid progression and
poor/unsatisfactory outcomes. In the past few years, the focus has been on developing …

Epithelial ovarian cancer (EOC) remains one of the most lethal gynecological cancers.
Cytokine-induced memory–like (CIML) natural killer (NK) cells have shown promising results …

Introduction Natural killer (NK) cells are a key component of the innate immune system,
involved in defending the host against virus-infected cells and tumor immunosurveillance …

In recent years, immunotherapy has become a powerful therapeutic option against multiple
malignancies. The unique capacity of natural killer (NK) cells to attack cancer cells without …

Introduction The curative basis of allogeneic hematopoietic stem cell transplantation (HSCT)
relies in part upon the graft versus leukemia (GvL) effect, whereby donor immune cells …

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy
for many hematologic malignancies as well as non-malignant conditions. Part of the curative …

Chimeric antigen receptor (CAR) T cells have been successfully used in adoptive cell
therapy for malignancies. However, some obstacles, including side effects such as graft …