Introduction Although tremendous progress has been made since the introduction of
allogeneic hematopoietic stem cell transplantation (HSCT) decades ago, there are still many …

NK cell therapeutics have gained significant attention as a potential cancer treatment.
Towards therapeutic use, NK cells need to be activated and expanded to attain high potency …

Allogeneic hematopoietic cell transplantation (HCT) has transformed over the past several
decades through enhanced supportive care, reduced intensity conditioning (RIC), improved …

Adoptive cellular therapy (ACT) using memory-like (ML) natural killer (NK) cells, generated
through overnight ex vivo activation with IL-12, IL-15, and IL-18, has shown promise for …

Small extracellular vesicles (sEV) derived from diverse natural killer (NK) cell lines have
proven their exceptional antitumor activities. However, sEV from human primary NK cells …

GvHD still remains, despite the continuous improvement of transplantation platforms, a
fearful complication of transplantation from allogeneic donors. Being able to separate GvHD …

Since researchers first began to uncover the mechanisms underlying allogeneic
transplantation, the focus has been on T cells. T cells are a major instigator of graft-versus …

Healthcare and nutrition are facing a paradigm shift in light of advanced therapy medicinal
products (ATMPs) and cellular agriculture options respectively. Both options heavily rely on …

Abstract Non-Hodgkin lymphomas (NHLs) are heterogeneous and are among the most
common hematological malignancies worldwide. Despite the advances in the treatment of …

Abstract Introduction The 2023 Coffey‐Holden Prostate Cancer Academy (CHPCA) Meeting,
themed “Disrupting Prostate Cancer Research: Challenge Accepted,” was convened at the …