Ferroptosis, necroptosis, and pyroptosis in the tumor microenvironment: Perspectives for immunotherapy of SCLC
X Niu, L Chen, Y Li, Z Hu, F He - Seminars in Cancer Biology, 2022 - Elsevier
Small cell lung cancer (SCLC) is an aggressive form of lung cancer characterized by dismal
prognosis. Although SCLC may initially respond well to platinum-based chemotherapy, it …
prognosis. Although SCLC may initially respond well to platinum-based chemotherapy, it …
Small cell lung cancer transformation: From pathogenesis to treatment
X Yin, Y Li, H Wang, T Jia, E Wang, Y Luo, Y Wei… - seminars in Cancer …, 2022 - Elsevier
Small cell lung cancer (SCLC) is a type of neuroendocrine tumor with high malignancy and
poor prognosis. Besides the de novo SCLC, there is transformed SCLC, which has similar …
poor prognosis. Besides the de novo SCLC, there is transformed SCLC, which has similar …
FOXM1: A small fox that makes more tracks for cancer progression and metastasis
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
RNA-based therapies: a cog in the wheel of lung cancer defense
Lung cancer (LC) is a heterogeneous disease consisting mainly of two subtypes, non-small
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …
POU2AF2/C11orf53 functions as a coactivator of POU2F3 by maintaining chromatin accessibility and enhancer activity
AP Szczepanski, N Tsuboyama, J Watanabe… - Science …, 2022 - science.org
Small cell lung cancer (SCLC), accounting for around 13% of all lung cancers, often results
in rapid tumor growth, early metastasis, and acquired therapeutic resistance. The POU class …
in rapid tumor growth, early metastasis, and acquired therapeutic resistance. The POU class …
[HTML][HTML] Small cell lung cancer: novel treatments beyond immunotherapy
JJ Meijer, A Leonetti, G Airò, M Tiseo, C Rolfo… - Seminars in cancer …, 2022 - Elsevier
Small cell lung cancer (SCLC) arises in peribronchial locations and infiltrates the bronchial
submucosa, including about 15% of lung cancer cases. Despite decades of research, the …
submucosa, including about 15% of lung cancer cases. Despite decades of research, the …
m6A regulators as predictive biomarkers for chemotherapy benefit and potential therapeutic targets for overcoming chemotherapy resistance in small-cell lung cancer
Z Zhang, C Zhang, Z Yang, G Zhang, P Wu… - Journal of Hematology & …, 2021 - Springer
Small-cell lung cancer (SCLC) is a devastating subtype of lung cancer with few therapeutic
options. Despite the advent of immunotherapy, platinum-based chemotherapy is still the …
options. Despite the advent of immunotherapy, platinum-based chemotherapy is still the …
Emerging role of chemokines in small cell lung cancer: Road signs for metastasis, heterogeneity, and immune response
Small cell lung cancer (SCLC) is a recalcitrant, relatively immune-cold, and deadly subtype
of lung cancer. SCLC has been viewed as a single or homogenous disease that includes …
of lung cancer. SCLC has been viewed as a single or homogenous disease that includes …
MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis
Background Small cell lung cancer (SCLC) is an aggressive lung cancer subtype that is
associated with high recurrence and poor prognosis. Due to lack of potential drug targets …
associated with high recurrence and poor prognosis. Due to lack of potential drug targets …
Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer
N Tsuboyama, R Wang, AP Szczepanski, H Chen… - Oncogene, 2022 - nature.com
Small cell lung cancer (SCLC) is an aggressive disease, with patients diagnosed with either
early-stage, limited stage, or extensive stage of SCLC tumor progression. Discovering and …
early-stage, limited stage, or extensive stage of SCLC tumor progression. Discovering and …