Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors

DQ Huang, P Mathurin, H Cortez-Pinto… - Nature reviews …, 2023 - nature.com
Heavy alcohol consumption is a major cause of morbidity and mortality. Globally, alcohol per-
capita consumption rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to …

The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TH Karlsen, N Sheron, S Zelber-Sagi, P Carrieri… - The Lancet, 2022 - thelancet.com
Executive summary Liver diseases have become a major health threat across Europe, and
the face of European hepatology is changing due to the cure of viral hepatitis C and the …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

CPG Panel, A Berzigotti, E Tsochatzis, J Boursier… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

Microbiome-derived ethanol in nonalcoholic fatty liver disease

AS Meijnikman, M Davids, H Herrema, O Aydin… - Nature medicine, 2022 - nature.com
To test the hypothesis that the gut microbiota of individuals with nonalcoholic fatty liver
disease (NAFLD) produce enough ethanol to be a driving force in the development and …

[HTML][HTML] Non-alcoholic fatty liver disease: A patient guideline

SM Francque, G Marchesini, A Kautz, M Walmsley… - JHEP reports, 2021 - Elsevier
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …

[HTML][HTML] Epidemiology of non-alcoholic and alcoholic fatty liver diseases

S Mitra, A De, A Chowdhury - Translational gastroenterology and …, 2020 - ncbi.nlm.nih.gov
Liver diseases are fast emerging as global health priorities. Fatty liver is described in the
setting of non-alcoholic fatty liver disease (NAFLD) as well as alcoholic liver disease (ALD) …

Coronavirus disease 2019 hangover: a rising tide of alcohol use disorder and alcohol‐associated liver disease

BL Da, GY Im, TD Schiano - Hepatology, 2020 - journals.lww.com
Abstract The coronavirus disease 2019 (COVID‐19) pandemic has had a tremendous global
impact since it began in November of 2019. However, there are concerns that the COVID‐19 …

[HTML][HTML] MAFLD: How is it different from NAFLD?

C Gofton, Y Upendran, MH Zheng… - Clinical and molecular …, 2023 - ncbi.nlm.nih.gov
Abstract “Metabolic dysfunction-associated fatty liver disease (MAFLD)” is the term
suggested in 2020 to refer to fatty liver disease related to systemic metabolic dysregulation …

Silymarin as supportive treatment in liver diseases: A narrative review

A Gillessen, HHJ Schmidt - Advances in therapy, 2020 - Springer
Silymarin, an extract from milk thistle seeds, has been used for centuries to treat hepatic
conditions. Preclinical data indicate that silymarin can reduce oxidative stress and …

Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of …

J Neuberger, J Patel, H Caldwell, S Davies, V Hebditch… - Gut, 2020 - gut.bmj.com
Liver biopsy is required when clinically important information about the diagnosis, prognosis
or management of a patient cannot be obtained by safer means, or for research purposes …