Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …

Radiation therapy is one of the most widely used therapies for malignancies. The
therapeutic use of heavy ions, such as carbon, has gained significant interest due to …

Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

Radiotherapy should have low toxicity in the entrance channel (normal tissue) and be very
effective in cell killing in the target region (tumour). In this regard, ions heavier than protons …

Background The comparative risks of a second cancer diagnosis are uncertain after primary
cancer treatment with 3‐dimensional conformal radiotherapy (3DCRT), intensity‐modulated …

Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …

Treatment of cancer patients with charged particles like proton and carbon ions landmarks a
new era in high-precision medicine. This review aims to summarize the physical and …

The radiation exposure of individuals has been on the rise due to an increased amount of
radiation use, eg, in medicine for diagnostic imaging and treatment procedures, industrial …

Research into high linear energy transfer (LET) radiotherapy now spans over half a century,
beginning with helium and deuteron treatment in 1952 and today ranging from fast neutrons …

Particle therapy is a promising and evolving modality of radiotherapy that can be used to
treat tumors that are radioresistant to conventional photon beam radiotherapy. It has unique …