DNA–protein interactions are involved in many essential biological activities. Because there
is no simple mapping code between DNA base pairs and protein amino acids, the prediction …

The channel structure of the Ku protein elegantly reveals the mechanistic basis of sequence-
independent DNA-end binding, which is essential to genome integrity after exposure to …

BRCA1 C-terminal domain (BRCT)-containing proteins are found widely throughout the
animal and bacteria kingdoms where they are exclusively involved in cell cycle regulation …

The elucidation of molecular interaction networks is one of the pivotal challenges in the
study of biology. Affinity purification—mass spectrometry and other co‐complex methods …

Background GabR is a transcriptional regulator belonging to the MocR/GabR family,
characterized by a N-terminal wHTH DNA-binding domain and a C-terminal effector binding …

We studied the molecular details of DNA aptamer–ricin interactions. The toxic protein ricin
molecules were immobilized on a Au (111) surface using a N-hydroxysuccinimide (NHS) …

HlyU, a transcriptional regulator common in many Vibrio species, activates the hemolysin
gene hlyA in Vibrio cholerae, the rtxA1 operon in Vibrio vulnificus and the genes of plp-vah1 …

Single molecule recognition imaging and dynamic force spectroscopy (DFS) analysis
showed strong binding affinity between an aptamer and ricin, which was comparable with …

Accurate identification of transcription factor binding sites is critical to our understanding of
transcriptional regulatory networks. To overcome the issue of high false-positive predictions …

Coarse grain modelling of macromolecules is a new approach, potentially well adapted to
answer numerous issues, ranging from physics to biology. We propose here an original …