Orchestrated cytokines mediated by biologics in psoriasis and its mechanisms of action
Psoriasis is an autoimmune disease mediated by disturbed T cells and other immune cells,
and is defined by deep-red, well-demarcated skin lesions. Due to its varied etiologies and …
and is defined by deep-red, well-demarcated skin lesions. Due to its varied etiologies and …
Fisetin, a 3, 7, 3′, 4′-tetrahydroxyflavone inhibits the PI3K/Akt/mTOR and MAPK pathways and ameliorates psoriasis pathology in 2D and 3D organotypic human …
Psoriasis is a chronic immune-mediated skin disease that involves the interaction of immune
and skin cells, and is characterized by cytokine-driven epidermal hyperplasia, deviant …
and skin cells, and is characterized by cytokine-driven epidermal hyperplasia, deviant …
Trends in nanotechnology-based delivery systems for dermal targeting of drugs: An enticing approach to offset psoriasis
Introduction Psoriasis is identified as an inflammatory, chronic, auto-immune disease
requiring long-term treatment, imposing an unnecessary burden on the patient. A significant …
requiring long-term treatment, imposing an unnecessary burden on the patient. A significant …
Role of neuroimmune circuits and pruritus in psoriasis
MT Ayasse, J Buddenkotte, M Alam… - Experimental …, 2020 - Wiley Online Library
Psoriasis is a chronic inflammatory skin disease presenting with an array of clinical
phenotypes, often associated with pruritus. Environmental and psychological stressors can …
phenotypes, often associated with pruritus. Environmental and psychological stressors can …
Psoriasis and cardiovascular disease: novel mechanisms and evolving therapeutics
Abstract Purpose of Review Psoriasis is a chronic inflammatory skin condition that is
associated with increased cardiovascular risk compared to those without psoriasis. This …
associated with increased cardiovascular risk compared to those without psoriasis. This …
New onset and exacerbation of psoriasis following COVID-19 vaccination: a review of the current knowledge
L Potestio, T Battista, S Cacciapuoti, A Ruggiero… - Biomedicines, 2023 - mdpi.com
COVID-19 vaccination was the main measure to overcome the pandemic. As with other
drugs and vaccines, mild to moderate adverse events have been reported following …
drugs and vaccines, mild to moderate adverse events have been reported following …
[HTML][HTML] Cluster analysis of circulating plasma biomarkers in prurigo nodularis reveals a distinct systemic inflammatory signature in African Americans
N Sutaria, MP Alphonse, M Marani… - Journal of Investigative …, 2022 - Elsevier
Patients with prurigo nodularis (PN) suffer from intractable itch and dramatic reduction in
QOL. Although there is significant clinical heterogeneity in the presentation of PN, disease …
QOL. Although there is significant clinical heterogeneity in the presentation of PN, disease …
Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance
WR Swindell, HA Remmer, MK Sarkar, X Xing… - Genome medicine, 2015 - Springer
Background Psoriasis is a chronic disease characterized by the development of scaly red
skin lesions and possible co-morbid conditions. The psoriasis lesional skin transcriptome …
skin lesions and possible co-morbid conditions. The psoriasis lesional skin transcriptome …
Association of Psoriasis with Anxiety and Depression: A Case–Control Study in Chinese Patients
Background: Patients with psoriasis are prone to suffer from anxiety and depression during
their lifetime. This study aimed to investigate the association of psoriasis with anxiety and …
their lifetime. This study aimed to investigate the association of psoriasis with anxiety and …
[HTML][HTML] Breaking the barrier-potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels
M Giulbudagian, G Yealland, S Hönzke, A Edlich… - Theranostics, 2018 - ncbi.nlm.nih.gov
Topical administration permits targeted, sustained delivery of therapeutics to human skin.
Delivery to the skin, however, is typically limited to lipophilic molecules with molecular …
Delivery to the skin, however, is typically limited to lipophilic molecules with molecular …