Genistein—opportunities related to an interesting molecule of natural origin

E Garbiec, J Cielecka-Piontek, M Kowalówka… - Molecules, 2022 - mdpi.com
Nowadays, increasingly more attention is being paid to a holistic approach to health, in
which diet contributes to disease prevention. There is growing interest in functional food that …

Tazarotene-calcipotriol loaded Nanostructured lipid carrier enriched hydrogel: a novel dual drug synergistic approach towards Psoriasis management

S Thakur, MM Anjum, S Jaiswal, AK Gautam… - Journal of Drug Delivery …, 2023 - Elsevier
Psoriasis with unclear etiology and pathogenesis is one of the most prevalent chronic skin
diseases. It involves excessive keratinocytes cells hyperproliferation, abnormal vascular …

Emerging trends in combination strategies with phototherapy in advanced psoriasis management

R Sreya, S Nene, V Pathade, SB Singh… - …, 2023 - Springer
Psoriasis is a non-contagious, chronic, relapsing inflammatory skin disease with cutaneous
manifestations such as red, raised scaly plaques. Current treatment approaches for …

Changes in proteome of fibroblasts isolated from psoriatic skin lesions

A Gęgotek, P Domingues, A Wroński… - International journal of …, 2020 - mdpi.com
The dermal fibroblasts are in constant contact with the cells of the immune system and skin
epidermis. Therefore, they are essential for the development of lesions in psoriasis. The aim …

Skin immunity and tolerance: focus on epidermal keratinocytes expressing HLA-G

G Mestrallet, N Rouas-Freiss, J LeMaoult… - Frontiers in …, 2021 - frontiersin.org
Although the role of epidermal cells in skin regeneration has been extensively documented,
their functions in immunity and tolerance mechanisms are largely underestimated. The aim …

NRF2, a crucial modulator of skin cells protection against vitiligo, psoriasis, and cancer

E Panieri, P Telkoparan‐Akillilar, L Saso - BioFactors, 2023 - Wiley Online Library
The skin represents a physical barrier between the organism and the environment that has
evolved to confer protection against biological, chemical, and physical insults. The inner …

[PDF][PDF] Nutritional strategies for psoriasis: current scientific evidence in clinical trials.

E Zuccotti, M Oliveri, D Ratto, C Di Iorio… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Several nutritional strategies for the management of psoriasis are promising.
Even if recent data support that nutrition may play a pivotal role in prevention and co …

Therapeutic development based on the immunopathogenic mechanisms of psoriasis

JC Tseng, YC Chang, CM Huang, LC Hsu, TH Chuang - Pharmaceutics, 2021 - mdpi.com
Psoriasis, a complex inflammatory autoimmune skin disorder that affects 2–3% of the global
population, is thought to be genetically predetermined and induced by environmental and …

The TULIP superfamily of eukaryotic lipid-binding proteins as a mediator of lipid sensing and transport

V Alva, AN Lupas - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2016 - Elsevier
The tubular lipid-binding (TULIP) superfamily has emerged in recent years as a major
mediator of lipid sensing and transport in eukaryotes. It currently encompasses three protein …

[HTML][HTML] Staphylococcus aureus colonization is increased on lupus skin lesions and is promoted by IFN-mediated barrier disruption

S Sirobhushanam, N Parsa, TJ Reed… - Journal of Investigative …, 2020 - Elsevier
Cutaneous inflammation is recurrent in systemic lupus erythematosus (SLE), yet
mechanisms that drive cutaneous inflammation in SLE are not well defined. Type I IFNs are …