Neurodegenerative diseases cause progressive loss of cognitive and/or motor function and
pose major challenges for societies with rapidly aging populations. Human genetics studies …

Aging is defined as a progressive time‐related accumulation of changes responsible for or
at least involved in the increased susceptibility to disease and death. The brain seems to be …

Imidacloprid (IMI) is a neonicotinoid compound widely used in agriculture production,
causing surface water pollution and threatening non-target organisms. The aim of this study …

Mitochondrial fragmentation due to imbalanced fission and fusion of mitochondria is a
prerequisite for mitophagy, however, the exact “coupling” of mitochondrial dynamics and …

Iron dyshomeostasis can cause neuronal damage to iron-sensitive brain regions.
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …

Selective autophagy of mitochondria, known as mitophagy, is an important mitochondrial
quality control mechanism that eliminates damaged mitochondria. Mitophagy also mediates …

Although aging is a known risk factor for idiopathic pulmonary fibrosis (IPF), the pathogenic
mechanisms that underlie the effects of advancing age remain largely unexplained. Some …

Mitochondrial autophagy, or mitophagy, is a major mechanism involved in mitochondrial
quality control via selectively removing damaged or unwanted mitochondria. Interactions …

Mitochondrial dysfunction and synaptic damage are early pathological features of the
Alzheimer's disease-affected brain. Memory impairment in Alzheimer's disease is a …

Mitochondria are organelles central to myriad cellular processes. To maintain mitochondrial
health, various processes co-operate at both the molecular and organelle level. At the …