Fluid management for sepsis-induced hypotension in patients with advanced chronic kidney disease: a secondary analysis of the CLOVERS trial

A Jorda, IS Douglas, T Staudinger, G Heinz… - Critical Care, 2024 - Springer
Background Early fluid management in patients with advanced chronic kidney disease
(CKD) and sepsis-induced hypotension is challenging with limited evidence to support …

Inhibitory immune checkpoints predict 7-day, in-hospital and 1-year mortality of internal medicine patients admitted with bacterial sepsis

F Mearelli, A Nunnari, A Rombini, F Chitti… - The Journal of …, 2024 - academic.oup.com
Background Sepsis is a life-threatening syndrome with complex pathophysiology and great
clinical heterogeneity which complicates the delivery of personalized therapies. Our goals …

Astrocytic HILPDA promotes lipid droplets generation to drive cognitive dysfunction in mice with sepsis‐associated encephalopathy

L Li, D Lixia, G Gan, J Li, L Yang, Y Wu… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims Sepsis‐associated encephalopathy (SAE) is manifested as a spectrum of disturbed
cerebral function ranging from mild delirium to coma. However, the pathogenesis of SAE has …

Improving Intestinal Barrier Function in Sepsis by Partially Hydrolysed Guar Gum via the Suppression of the NF-κB/MLCK Pathway

Z Tang, Y Zhu, X Hu, K Lui, S Li, X Song, C Cai… - Molecular …, 2024 - Springer
Partially hydrolyzed guar gum (PHGG) protects against intestinal barrier dysfunction and can
ameliorate some intestinal diseases. However, whether PHGG has a role in protecting …

Costs and Resources Must Impact Clinical Decision-Making in the ICU: The Case of Vasopressor Use

SR Bauer, JW Devlin - Critical Care Medicine, 2024 - journals.lww.com
Medication-related costs account for 17.7% of total ICU charges and continue to increase
over time (1). Vasopressors are one medication class where acquisition costs in the United …

大鼠严重腹腔感染后脾脏细胞周期的变化

李晋平, 刘汉卿, 杨全会 - 基础医学与临床, 2024 - journal11.magtechjournal.com
目的探讨大鼠腹腔感染时动物的死亡率, 脾脏细胞周期和细胞凋亡的变化.
方法采用盲肠结扎穿孔术(CLP) 制备大鼠腹腔感染的动物模型, 计算术后0 h, 6 h, 12 h, 24 h, 48 …

Perspective: Sepsis Biomarker Research Requires a Move to the Emergency Department and More Collaboration

AE Fox-Robichaud, J Arora - Medical Research Archives, 2024 - esmed.org
Despite years of research and multiple potential candidate biomarkers for sepsis, few have
had sufficient sensitivity or specificity to be integrated into routine practice. There have been …

Change of cell cycle in rat spleen after severe abdominal infection

J LI, H LIU, Q YANG - Basic & Clinical Medicine, 2024 - journal11.magtechjournal.com
Objective To explore the mortality rate and changes in splenic cell cycle and apoptosis in
rats with abdominal infection. Methods An animal model of sepsis was induced by cecal …

Analisi delle prescrizioni e verifica dell'utilizzo di albumina umana presso un presidio ospedaliero.

S MORATI - thesis.unipd.it
Il progetto intende valutare il corretto utilizzo di albumina umana all'interno dei reparti del
presidio ospedaliero" Casa di cura Pederzoli". Attraverso le richieste motivate per …