Diazirine based photoaffinity labeling
L Dubinsky, BP Krom, MM Meijler - Bioorganic & medicinal chemistry, 2012 - Elsevier
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon
light irradiation. This feature has been widely utilized in photoaffinity labeling to study ligand …
light irradiation. This feature has been widely utilized in photoaffinity labeling to study ligand …
Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques
Sterol regulatory element-binding proteins (SREBPs) are major transcription factors
activating the expression of genes involved in biosynthesis of cholesterol, fatty acid and …
activating the expression of genes involved in biosynthesis of cholesterol, fatty acid and …
Synthesis of S‐Adenosyl‐L‐homocysteine Capture Compounds for Selective Photoinduced Isolation of Methyltransferases
C Dalhoff, M Hüben, T Lenz, P Poot, E Nordhoff… - …, 2010 - Wiley Online Library
Understanding the interplay of different cellular proteins and their substrates is of major
interest in the postgenomic era. For this purpose, selective isolation and identification of …
interest in the postgenomic era. For this purpose, selective isolation and identification of …
Development of trifunctional probes for glycoproteomic analysis
C Tsai, PY Liu, HY Yen, TL Hsu… - Chemical communications, 2010 - pubs.rsc.org
Development of trifunctional probes for glycoproteomic analysis - Chemical Communications
(RSC Publishing) DOI:10.1039/C0CC00345J Royal Society of Chemistry View PDF …
(RSC Publishing) DOI:10.1039/C0CC00345J Royal Society of Chemistry View PDF …
Chemical proteomic study of isoprenoid chain interactome with a synthetic photoaffinity probe
A chemical proteomic approach was developed for profiling the noncovalent interactome of
isoprenoid chain in the yeast proteome. A chemical probe that harbors a biotin moiety and a …
isoprenoid chain in the yeast proteome. A chemical probe that harbors a biotin moiety and a …
[PDF][PDF] 9.14 Modern Methods for the Isolation of Natural Product Receptors
P Karuso - Comprehensive Natural Products II - pharmacy.hebmu.edu.cn
Humans have probably made use of natural products for tens of thousands of years.
Certainly, by the time writing was invented the human pharmacopeia already contained …
Certainly, by the time writing was invented the human pharmacopeia already contained …
Fluorinated Three‐Membered Ring Heterocycles
DM Lemal, S Ramanathan - … Compounds: Synthesis, Chemistry …, 2009 - Wiley Online Library
Highly fluorinated oxiranes contrast sharply with their hydrocarbon counterparts with regard
to both methods for their synthesis and chemical reactivity. Hydrocarbonderived oxiranes …
to both methods for their synthesis and chemical reactivity. Hydrocarbonderived oxiranes …
Design and synthesis of azobenzene template based sulfonamide for capture of HCAII: dependence of efficiency on E–Z geometry
We report the synthesis of azobenzene template based sulfonamides 1 and 2 for capture of
Human Carbonic Anhydrase II (HCAII). Out of these, 1 showed successful capturing of the …
Human Carbonic Anhydrase II (HCAII). Out of these, 1 showed successful capturing of the …
[图书][B] Synthetic studies on apoptolidin congeners in support of target identification of a cell selective cytotoxic agent
J Wang - 2009 - search.proquest.com
As reported by the American Cancer Society, 7.6 million people died of various cancers in
2007 (http://www. cancer. org), cancer is one of the leading causes of morality worldwide …
2007 (http://www. cancer. org), cancer is one of the leading causes of morality worldwide …