The epidermal growth factor receptor (EGFR) family contains four transmembrane tyrosine
kinases (EGFR1/ErbB1, Her2/ErbB2, Her3/ErbB3 and Her4/ErbB4) and 13 secreted …

Cancer is a leading cause of death worldwide and cancer incidence and mortality are
rapidly growing. These massive amounts of cancer patients require rapid diagnosis and …

Correlative clinical evidence and experimental observations indicate that integrin adhesion
receptors, in particular those of the αV family, are relevant to cancer cell features, including …

Endometriosis is an estrogen-dependent inflammatory disease that affects up to 10% of
women of reproductive age and accounts for up to 50% of female infertility cases. It has …

Triple-negative breast cancer (TNBC) is not as prevalent as hormone receptor or HER2-
positive breast cancers and all receptor tests come back negative. More importantly, the …

The inflammatory Bowel diseases (IBDs) are a chronic, relapsing inflammatory diseases of
the gastrointestinal tract with heterogeneous behavior and prognosis. The introduction of …

Diabetic ulcers (DUs) are one of the most serious complications of diabetes mellitus. The
application of a functional dressing is a crucial step in DU treatment and is associated with …

Simple Summary Immunotherapies and molecularly targeted therapies have drastically
changed the therapeutic approach for unresectable advanced or metastatic melanoma. The …

viii everybody who contributed to the first edition. As always, I have to thank my wife and
family for encouragement and support (as well as patience…). I hope you will find this book …

Cytotoxic chemotherapy is the major strategy to prevent and reduce triple-negative breast
cancer (TNBC) progression and metastasis. Hypoxia increases chemoresistance and is …