Antibiotic resistance is a serious threat to public health. Significant efforts are currently
directed toward containment of the spread of resistance, finding new therapeutic options …

Microorganisms need to constantly exchange with their habitat to capture nutrients and
expel toxic compounds. The ATP-binding cassette (ABC) transporters, a family of membrane …

ATP-binding cassette (ABC) transporters, a superfamily of integral membrane proteins,
catalyse the translocation of substrates across the cellular membrane by ATP hydrolysis …

MsbA is an essential ATP-binding cassette half-transporter in the cytoplasmic membrane of
the gram-negative Escherichia coli and is required for the export of lipopolysaccharides …

ATP-binding cassette transporters are ubiquitous in almost all organisms. The Escherichia
coli genome is predicted to encode 69 ABC transporters. Eleven of the ABC transporters are …

For the brain to operate normally and to develop with structural integrity in addition to
neuronal function, blood-brain barrier present in brain capillaries serves as a vital barrier …

Multidrug resistance (MDR)-type transporters mediate the active extrusion of structurally and
functionally dissimilar compounds from the cells, thereby rendering cells resistant to a range …

The countries' cultural legacy is one of the world's most diverse. It is a beacon that draws
millions every year to our convents and monuments, to our museums and libraries, as well …

About 50% of the world's arable land is strongly acidic (pH≤ 5). The low pH solubilizes root-
toxic ionic aluminium (Al3+) species from clay minerals, driving the evolution of …

ATP-binding-cassette (ABC) multidrug transporters confer multidrug resistance to
pathogenic microorganisms and human tumour cells by mediating the extrusion of …