Gastroenteropancreatic neuroendocrine tumors
M Cives, JR Strosberg - CA: a cancer journal for clinicians, 2018 - Wiley Online Library
Neuroendocrine tumors (NETs) are heterogeneous malignancies arising from the diffuse
neuroendocrine system. They frequently originate in the gastroenteropancreatic (GEP) tract …
neuroendocrine system. They frequently originate in the gastroenteropancreatic (GEP) tract …
[HTML][HTML] Nothing but NET: a review of neuroendocrine tumors and carcinomas
B Oronsky, PC Ma, D Morgensztern, CA Carter - Neoplasia, 2017 - Elsevier
This review covers the diverse topic of neuroendocrine neoplasms (NENs), a relatively rare
and heterogeneous tumor type, comprising~ 2% of all malignancies, with a prevalence of< …
and heterogeneous tumor type, comprising~ 2% of all malignancies, with a prevalence of< …
Surufatinib in advanced extrapancreatic neuroendocrine tumours (SANET-ep): a randomised, double-blind, placebo-controlled, phase 3 study
J Xu, L Shen, Z Zhou, J Li, C Bai, Y Chi, Z Li… - The Lancet …, 2020 - thelancet.com
Background Therapeutic options for advanced neuroendocrine tumours (NETs) are limited.
We investigated the efficacy and safety of surufatinib (HMPL-012, sulfatinib) in patients with …
We investigated the efficacy and safety of surufatinib (HMPL-012, sulfatinib) in patients with …
DAXX in cancer: phenomena, processes, mechanisms and regulation
DAXX displays complex biological functions. Remarkably, DAXX overexpression is a
common feature in diverse cancers, which correlates with tumorigenesis, disease …
common feature in diverse cancers, which correlates with tumorigenesis, disease …
[HTML][HTML] Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
A Di Domenico, CP Pipinikas, RS Maire… - Communications …, 2020 - nature.com
Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α-
or β-cells of the islets of Langerhans. The majority of PanNETs are non-functional and do not …
or β-cells of the islets of Langerhans. The majority of PanNETs are non-functional and do not …
[HTML][HTML] Epigenetic regulation of somatostatin and somatostatin receptors in neuroendocrine tumors and other types of cancer
MJ Klomp, SU Dalm, M De Jong, RA Feelders… - Reviews in Endocrine …, 2021 - Springer
Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …
[HTML][HTML] An update on the diagnosis of gastroenteropancreatic neuroendocrine neoplasms
JM Fang, J Li, J Shi - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) arise from neuroendocrine
cells found throughout the gastrointestinal tract and islet cells of the pancreas. The incidence …
cells found throughout the gastrointestinal tract and islet cells of the pancreas. The incidence …
[HTML][HTML] The landscape of molecular alterations in pancreatic and small intestinal neuroendocrine tumours
A Scarpa - Annales d'endocrinologie, 2019 - Elsevier
Abstract Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs) arise throughout
the gut and feature varying biological behaviour and malignant potential. GEP-NENs include …
the gut and feature varying biological behaviour and malignant potential. GEP-NENs include …
[HTML][HTML] Gastrinoma
RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …
Prognostic and predictive factors on overall survival and surgical outcomes in pancreatic neuroendocrine tumors: recent advances and controversies
L Lee, T Ito, RT Jensen - Expert review of anticancer therapy, 2019 - Taylor & Francis
Introduction: Recent advances in diagnostic modalities and therapeutic agents have raised
the importance of prognostic factors in predicting overall survival, as well as predictive …
the importance of prognostic factors in predicting overall survival, as well as predictive …