[HTML][HTML] Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny

LDW Luu, V Kasimov, S Phillips, GSA Myers… - Frontiers in cellular …, 2023 - frontiersin.org
The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals, including C. trachomatis and C. pneumoniae. Since 1998, when the …

[HTML][HTML] The role of infected epithelial cells in Chlamydia-associated fibrosis

LT Caven, RA Carabeo - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Ocular, genital, and anogenital infection by the obligate intracellular pathogen Chlamydia
trachomatis have been consistently associated with scar-forming sequelae. In cases of …

Metabolic model guided CRISPRi identifies a central role for phosphoglycerate mutase in Chlamydia trachomatis persistence

NB Chowdhury, N Pokorzynski, EA Rucks… - Msystems, 2024 - journals.asm.org
Upon nutrient starvation, Chlamydia trachomatis serovar L2 (CTL) shifts from its normal
growth to a non-replicating form, termed persistence. It is unclear if persistence reflects an …

Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance

B Lu, Y Wang, W Wurihan, A Cheng, S Yeung… - Mbio, 2024 - Am Soc Microbiol
Chlamydia, an obligate intracellular bacterial pathogen, has a unique developmental cycle
involving the differentiation of invading elementary bodies (EBs) to noninfectious reticulate …