Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …

Therapeutic advances for neurological disorders are challenging due to limited accessibility
of the human central nervous system and incomplete understanding of disease …

Introduction Placenta-derived mesenchymal cells (PLCs) endogenously produce FVIII,
which makes them ideally suited for cell-based fVIII gene delivery. We have previously …

Organoids are self-organized, three-dimensional structures derived from stem cells that can
mimic the structure and physiology of human organs. Patient-specific induced pluripotent …

The use of animal models for biological experiments is no longer sufficient for research
related to human life and disease. The development of organ tissues has replaced animal …

Current knowledge of stem cell biology, as well as various cell culture technologies that
have been established in recent years, supports the field of developmental biology and …