Integrated molecular and immunological features of human T-lymphotropic virus type 1 infection and disease progression to adult T-cell leukaemia or lymphoma

JS O'Donnell, SK Hunt, KJ Chappell - The Lancet Haematology, 2023 - thelancet.com
The human T-lymphotropic virus type 1 (HTLV-1) retrovirus infects 10–20 million people
globally, with endemic regions in southwestern Japan, the Caribbean basin, Africa, and …

[HTML][HTML] BoLA-DRB3 polymorphism is associated with differential susceptibility to bovine leukemia virus-induced lymphoma and proviral load

CW Lo, L Borjigin, S Saito, K Fukunaga, E Saitou… - Viruses, 2020 - mdpi.com
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis. However,
less than 5% of BLV-infected cattle will develop lymphoma, suggesting that, in addition to …

[HTML][HTML] Milk Transmission of HTLV-1 and the need for innovative prevention strategies

S Millen, AK Thoma-Kress - Frontiers in Medicine, 2022 - frontiersin.org
Breastfeeding is recommended by the World Health Organization for at least 6 months up to
2 years of age, and breast milk protects against several diseases and infections. Intriguingly …

[HTML][HTML] The Global Epidemiology of Bovine Leukemia Virus: Current Trends and Future Implications

G Lv, J Wang, S Lian, H Wang, R Wu - Animals, 2024 - mdpi.com
Simple Summary Bovine leukemia virus (BLV) is the causative agent of enzootic bovine
leukosis (EBL), which is the most significant neoplastic disease in cattle. EBL is often …

Evaluating tocilizumab safety and immunomodulatory effects under ocular HTLV-1 infection in vitro

J Zhang, K Kamoi, Y Zong, M Yang, Y Zou… - International …, 2024 - Elsevier
There is growing interest in evaluating the safety and therapeutic potential of existing
treatments such as tocilizumab (TCZ), an IL-6 receptor antagonist used to treat inflammatory …

[HTML][HTML] Case report: relevance of an accurate diagnosis and monitoring of infective dermatitis associated with human T-lymphotropic virus type 1 in childhood

P Benencio, N Ducasa, L Arruvito, I Irurzun… - Frontiers in …, 2021 - frontiersin.org
Human T-lymphotropic virus type 1 (HTLV-1) is a neglected retrovirus distributed worldwide
and the ethiological agent of several pathologies, such as adult T-cell leukemia/lymphoma …

Frequency and characteristics of HTLV in migrants: Results from the+ Redivi collaborative network in Spain

FF Norman, F Salvador, B Gullón… - Journal of Travel …, 2022 - academic.oup.com
Introduction The objective of this study was to describe the main characteristics of migrants
diagnosed with human T-lymphotropic virus (HTLV) infection within the+ Redivi Spanish …

[HTML][HTML] Making Visible HTLV Infection in a Non-endemic Area of Argentina

FR Simioli, MB Bouzas, D Mijalovsky, MV Pineda… - Frontiers in …, 2022 - frontiersin.org
In Argentina, the human T-cell lymphotropic virus type 1 (HTLV-1) infection has been
documented mainly among blood banks with a prevalence of~ 0.02–0.046% for Buenos …

The association of polymorphisms (rs2227981 and rs10204525) of PDCD1 gene with susceptibility to human T-cell leukemia virus type 1

YA Hezave, Z Sharifi, M Shahabi - Microbial Pathogenesis, 2021 - Elsevier
Programmed cell death-1 (PD-1) is a regulatory protein that has an important role in immune
system response and created exhaustion phenotype in T cells at chronic infections; …

[HTML][HTML] Prevalence and characteristics of HTLV-associated uveitis in patients from Bahia, an endemic area for HTLV− 1 in Brazil

D Piai Ozores, R Rathsam Pinheiro, N Boa-Sorte… - Virology Journal, 2023 - Springer
Abstract Background HTLV-1-associated uveitis (HAU) is an inflammatory reaction of the
choroid, retina, optic nerve and vitreous that can lead to vision impairment. The worldwide …